SCHEMBL4591845

SCHEMBL4591845

CCCCCOC(C)(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.46
▸ CES2 O00748 3/20 0.46
▸ CES1 P23141 3/20 0.46
▸ TP53 P04637 2/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ LMNA P02545 2/20 0.45
▸ ALDH1A1 P00352 1/20 0.45
▸ NAAA Q02083 1/20 0.44
▸ TDP1 Q9NUW8 1/20 0.43
▸ PRSS1 P07477 1/20 0.43
▸ CTSG P08311 1/20 0.43
▸ CTRB1 P17538 1/20 0.43
▸ CMA1 P23946 1/20 0.43
▸ PLA2G4B P0C869 1/20 0.43
▸ PPARG P37231 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4629163 0.95 LMNA (0.46) TSHRCES2CES1TP53CYP3A4
SCHEMBL15381998 0.86 TSHR (0.47) TSHRCES2CES1TP53CYP3A4
SCHEMBL14514222 0.86 TSHR (0.47) TSHRCES2CES1TP53CYP3A4
SCHEMBL10384825 0.82 LMNA (0.46) TSHRCES2CES1TP53CYP3A4
SCHEMBL11768405 0.81 CES1 (0.45) TSHRCES2CES1TP53CYP3A4
SCHEMBL14237206 0.81 TSHR (0.46) TSHRCES2CES1TP53CYP3A4
SCHEMBL10942987 0.81 PPARA (0.46) TSHRCES2CES1TP53LMNA
SCHEMBL13754160 0.80 CES1 (0.55) TSHRCES2CES1TP53CYP3A4
SCHEMBL9303826 0.80 CES1 (0.55) TSHRCES2CES1TP53CYP3A4
SCHEMBL11083344 0.80 TDP1 (0.48) TSHRCES1MAPK1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9402793-B2 Use of UV-filters to stabilize resveratrol in topical cosmetic compositions DSM IP ASSETS B.V. (NL) 2016-08-02 — — US claimed
US-20130324616-A1 USE OF UV-FILTERS TO STABILIZE RESVERATROL IN TOPICAL COSMETIC COMPOSITIONS DSM IP ASSETS B.V. (NL) 2013-12-05 — — US claimed
US-20130315848-A1 COSMETIC COMPOSITION FOR SKIN WHITENING COMPRISING RESVERATROL DSM IP ASSETS B.V. (NL) 2013-11-28 — — US claimed
EP-2642972-A1 USE OF UV-FILTERS TO STABILIZE RESVERATROL IN TOPICAL COSMETIC COMPOSITIONS DSM IP Assets B.V. (NL) 2013-10-02 — — EP claimed
EP-2642973-A1 COSMETIC COMPOSITION FOR SKIN WHITENING COMPRISING RESVERATROL DSM IP Assets B.V. (NL) 2013-10-02 — — EP claimed
WO-2012069362-A1 COSMETIC COMPOSITION FOR SKIN WHITENING COMPRISING RESVERATROL DSM IP ASSETS B.V. (NL) 2012-05-31 — — WO claimed
WO-2012069363-A1 USE OF UV-FILTERS TO STABILIZE RESVERATROL IN TOPICAL COSMETIC COMPOSITIONS DSM IP ASSETS B.V. (NL) 2012-05-31 — — WO claimed
WO-2004062635-A1 COMPOSITIONS FOR SKIN LIGHTENING COMPRISING BIS-PANTOYL-CYSTAMINE DSM IP ASSETS B.V. (NL) 2004-07-29 — — WO claimed
CN-113616540-B Novel occlusive formulations 株式会社LG生活健康 2023-11-03 — — CN disclosed
CN-116634983-A Elastomeric gel from epoxidized vegetable oil and uses thereof 迈图高新材料公司 2023-08-22 — — CN disclosed
EP-3033066-B1 POLYUREA OR POLYURETHANE CAPSULES INT FLAVORS & FRAGRANCES INC (US) 2023-07-12 — — EP disclosed
EP-4209264-A1 MICROCAPSULE COMPOSITIONS STABILIZED WITH VISCOSITY CONTROL AGENTS International Flavors & Fragrances Inc. (US) 2023-07-12 — — EP disclosed
US-20230172820-A1 Compositions Containing Microcapsules INTERNATIONAL FLAVORS & FRAGRANCES INC. 2023-06-08 — — US disclosed
EP-3512625-B1 MICROCAPSULE COMPOSITIONS STABILIZED WITH VISCOSITY CONTROL AGENTS INT FLAVORS & FRAGRANCES INC (US) 2023-04-26 — — EP disclosed
CN-101415402-A UV-stable liquid or semisolid transdermal delivery form comprising a light-sensitive active ingredient SCHERING AKTI ENGESELLSCHAFT (DE) 2009-04-22 — — CN disclosed
US-7381769-B2 Cosmetic compositions using polyether siloxane copolymer network compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-06-03 — — US disclosed
CN-1826126-A Plant extract with prebiotic activity HENKEL KGAA (DE) 2006-08-30 — — CN disclosed
CN-1678339-A Synergistic combination of silk proteins HENKEL KGAA (DE) 2005-10-05 — — CN disclosed
US-20050197477-A1 Cosmetic compositions using polyether siloxane copolymer network compositions MOMENTIVE PERFORMANCE MATERIALS INC. 2005-09-08 — — US disclosed
WO-1992017159-A2 STABILIZED EMULSION COMPOSITIONS FOR IMPARTING AN ARTIFICIAL TAN TO HUMAN SKIN RICHARDSON-VICKS INC. (US) 1992-10-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172820-A1 Compositions Containing Microcapsules COPE, SAAL1, AUP1 TSHR 3290/4885CES2 2972/4885CES1 4331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback