Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709834 | 0.98 | PTGS2 (0.36) | PTGS2CYP3A4SLC6A2SLC6A4HTR2A | |
| SCHEMBL8469997 | 0.98 | PTGS2 (0.36) | PTGS2CYP3A4SLC6A2SLC6A4HTR2A | |
| SCHEMBL1778766 | 0.98 | PTGS2 (0.36) | PTGS2CYP3A4SLC6A2SLC6A4HTR2A | |
| SCHEMBL7646225 | 0.98 | PTGS2 (0.36) | PTGS2CYP3A4SLC6A2SLC6A4HTR2A | |
| SCHEMBL8574350 | 0.98 | PTGS2 (0.36) | PTGS2CYP3A4SLC6A2SLC6A4HTR2A | |
| SCHEMBL981813 | 0.94 | HTT (0.36) | HTTTP53TYRMAPT | |
| SCHEMBL1777552 | 0.86 | TSHR (0.31) | HSD17B10TSHR | |
| SCHEMBL11417292 | 0.83 | ACHE (0.33) | CYP1A2CYP2A6KDM4EACHEMAPT | |
| SCHEMBL5597590 | 0.81 | HRH1 (0.35) | CYP3A4HTR2ACYP1A2CYP2A6KCNH2 | |
| SCHEMBL1940072 | 0.81 | PTGS2 (0.37) | PTGS2CYP3A4SLC6A2SLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125543-A1 | Cationic Block Copolymers | NANOHALE GMBH (DE) | 2008-05-29 | — | — | US | claimed |
| US-20070036866-A1 | Cationic block copolymers | NANOHALE GMBH (DE) | 2007-02-15 | — | — | US | claimed |
| EP-1226204-B1 | CATIONIC BLOCK COPOLYMERS | MEDINNOVA GES MED INNOVATIONEN (DE) | 2006-01-11 | — | — | EP | claimed |
| CN-1364179-A | Cationic block copolymers | MEDINOVO MEDICAL STUDY AND INN (DE) | 2002-08-14 | — | — | CN | claimed |
| US-7351845-B2 | Transition metal polymerization catalysts, their synthesis and use in olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-04-01 | — | — | US | disclosed |
| US-20060173144-A1 | Transition metal polymerization catalysts, their synthesis and use in olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173144-A1 | Transition metal polymerization catalysts, their synthesis and use in olefin polymerization | SOD1, CCNT1, MYB | PTGS2 1030/4885CYP3A4 463/4885SLC6A2 4728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.