SCHEMBL4592018

SCHEMBL4592018

Fc1ccc([S+](c2ccc(F)c(F)c2)c2ccc(F)c(F)c2)cc1F

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
NFE2L2 Q16236 2/20 0.33
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
NOTUM Q6P988 1/20 0.31
CA3 P07451 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
RAPGEF4 Q8WZA2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24952545 0.78 CES2 (0.36) CES2CES1NFE2L2NOTUM
SCHEMBL4591796 0.76 MEN1 (0.41) RAPGEF4ALDH1A1HTT
SCHEMBL16182205 0.74 NFE2L2 (0.33) CES2CES1NFE2L2RAPGEF4
SCHEMBL30221878 0.74 NFE2L2 (0.33) CES2CES1NFE2L2RAPGEF4
SCHEMBL29603651 0.71 HDAC1 (0.36)
SCHEMBL29156409 0.67
SCHEMBL686201 0.65 CA1 (0.42) CES2CES1NFE2L2CA9
SCHEMBL29352228 0.65
SCHEMBL13741967 0.65 CYP17A1 (0.52) CES2CES1HSD17B1HSD17B2NOTUM
SCHEMBL180042 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230400768-A1 RADIATION-SENSITIVE COMPOSITION AND METHOD OF FORMING RESIST PATTERN JSR CORPORATION (JP) 2023-12-14 US disclosed
WO-2023157455-A1 RADIATION-SENSITIVE COMPOSITION AND METHOD FOR FORMING RESIST PATTERN JSR株式会社 2023-08-24 WO disclosed
US-20210389667-A9 RADIATION-SENSITIVE RESIN COMPOSITION AND RESIST PATTERN-FORMING METHOD JSR CORPORATION (JP) 2021-12-16 US disclosed
US-20210124263-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND RESIST PATTERN-FORMING METHOD JSR CORPORATION (JP) 2021-04-29 US disclosed
US-8110337-B2 Mixture of binder, an unsaturated compound and acid generator; lithography FUJIFILM CORPORATION (JP) 2012-02-07 US disclosed
US-7442485-B2 Lithographic process involving on press development FUJIFILM CORPORATION (JP) 2008-10-28 US disclosed
US-20070229637-A1 Ink set for ink-jet recording and ink-jet recording method FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
EP-1484177-B1 Lithographic process involving on press development FUJIFILM CORP (JP) 2007-08-29 EP disclosed
US-20050016402-A1 Lithographic process involving on press development FUJI PHOTO FILM CO., LTD. 2005-01-27 US disclosed
EP-1484177-A2 Lithographic process involving on press development FUJI PHOTO FILM CO., LTD. (JP) 2004-12-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210124263-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND RESIST PATTERN-FORMING METHOD RER1, RAD51, AFF1 CES2 2079/4885CES1 2454/4885NFE2L2 928/4885
US-20210389667-A9 RADIATION-SENSITIVE RESIN COMPOSITION AND RESIST PATTERN-FORMING METHOD RER1, RAD51, AFF1 CES2 2079/4885CES1 2454/4885NFE2L2 928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.