Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 10/20 | 0.42 |
| ▸ | PDE4A | P27815 | 4/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.35 |
| ▸ | TRPM5 | Q9NZQ8 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14144412 | 0.84 | REN (0.44) | RENPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2811635 | 0.80 | PTGER4 (0.45) | RENPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4253933 | 0.79 | REN (0.45) | REN | |
| SCHEMBL78487 | 0.76 | REN (0.52) | RENPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2805392 | 0.76 | REN (0.43) | RENPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL91360 | 0.75 | REN (0.44) | RENPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4732483 | 0.74 | REN (0.40) | RENPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14144409 | 0.73 | REN (0.42) | RENPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4582670 | 0.73 | REN (0.42) | RENPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4602445 | 0.73 | ICMT (0.44) | RENPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077917-A1 | PROCESS FOR PREPARING (R OR S)-2-ALKYL-3-HETEROCYCLYL-1-PROPANOLS | NOVARTIS AG (CH) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008055939-A2 | PROCESS FOR PREPARING 2-ALKYL-3-HETEROCYCLYL- PROP-2-EN- 1-OL DERIVATIVES | NOVARTIS AG (CH) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008055939-A2 | PROCESS FOR PREPARING 2-ALKYL-3-HETEROCYCLYL- PROP-2-EN- 1-OL DERIVATIVES | NOVARTIS AG (CH) | 2008-05-15 | — | — | WO | disclosed |
| EP-1921069-A1 | Process for preparing 2-alkyl-3-heterocyclyl-prop-2-en-1-ols | Speedel Experimenta AG (CH) | 2008-05-14 | — | — | EP | disclosed |
| EP-1921069-A1 | Process for preparing 2-alkyl-3-heterocyclyl-prop-2-en-1-ols | Speedel Experimenta AG (CH) | 2008-05-14 | — | — | EP | disclosed |