Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 5/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 4/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2805392 | 0.79 | REN (0.43) | RENCNR1CNR2PDE4APDE4B | |
| SCHEMBL91360 | 0.78 | REN (0.44) | RENCNR1CNR2PDE4APDE4B | |
| SCHEMBL4736285 | 0.78 | REN (0.44) | RENHRH3SLC22A12 | |
| SCHEMBL1050732 | 0.76 | REN (0.42) | RENCNR1CNR2PDE4APDE4B | |
| SCHEMBL13962829 | 0.76 | REN (0.42) | RENCNR1CNR2PDE4APDE4B | |
| SCHEMBL13962817 | 0.76 | REN (0.42) | RENCNR1CNR2PDE4APDE4B | |
| SCHEMBL4602445 | 0.76 | ICMT (0.44) | RENCNR1CNR2PDE4APDE4B | |
| SCHEMBL2811635 | 0.75 | PTGER4 (0.45) | RENCNR1CNR2PDE4APDE4B | |
| SCHEMBL13131404 | 0.75 | REN (0.41) | RENCNR1CNR2PDE4APDE4B | |
| SCHEMBL2935768 | 0.74 | SLC22A12 (0.58) | RENCNR1CNR2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008055939-A2 | PROCESS FOR PREPARING 2-ALKYL-3-HETEROCYCLYL- PROP-2-EN- 1-OL DERIVATIVES | NOVARTIS AG (CH) | 2008-05-15 | — | — | WO | disclosed |