Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223417 | 0.83 | CTRB1 (0.53) | CTRB1CTSLCTSSCA12CA1 | |
| SCHEMBL11283166 | 0.81 | CTRB1 (0.56) | CTRB1ALDH1A1CA12CA1CA2 | |
| SCHEMBL18576677 | 0.81 | CTRB1 (0.67) | CTRB1ALDH1A1CTSLCTSSCA12 | |
| SCHEMBL2353282 | 0.81 | CTRB1 (0.67) | CTRB1ALDH1A1CTSLCTSSCA12 | |
| SCHEMBL31089911 | 0.74 | CA2 (0.54) | CTRB1CTSLCTSSCA12CA1 | |
| SCHEMBL2749553 | 0.74 | PPARA (0.53) | CTRB1CTSLCTSSCA12CA1 | |
| SCHEMBL30629995 | 0.74 | CA2 (0.54) | CTRB1CTSLCTSSCA12CA1 | |
| SCHEMBL2102910 | 0.74 | CASP1 (0.52) | CTRB1ALDH1A1CTSLCTSSCA12 | |
| SCHEMBL19136379 | 0.74 | CA2 (0.54) | CTRB1CTSLCTSSCA12CA1 | |
| SCHEMBL5559459 | 0.74 | CTRB1 (0.51) | CTRB1ALDH1A1CTSLCTSSCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122661-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS (DE) | 2006-11-23 | — | — | WO | disclosed |