Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592329 | 0.78 | S1PR2 (0.31) | LMNASMN1; SMN2PTPN1S1PR2S1PR1 | |
| SCHEMBL600960 | 0.73 | GPR84 (0.39) | KMT2AMEN1MAPTNR1I2LMNA | |
| SCHEMBL31351898 | 0.72 | L3MBTL1 (0.43) | POLBKMT2AMEN1MAPTNR1I2 | |
| SCHEMBL10755910 | 0.71 | KMT2A (0.49) | POLBKMT2AMEN1MAPTNR1I2 | |
| SCHEMBL10383359 | 0.71 | CYP3A4 (0.47) | KMT2AMEN1MAPTNR1I2LMNA | |
| SCHEMBL19518041 | 0.70 | MEN1 (0.49) | POLBKMT2AMEN1MAPTNR1I2 | |
| SCHEMBL19817072 | 0.69 | L3MBTL1 (0.40) | POLBKMT2AMEN1MAPTNR1I2 | |
| SCHEMBL11874439 | 0.67 | L3MBTL1 (0.64) | KMT2AMEN1MAPTNR1I2LMNA | |
| SCHEMBL11662071 | 0.66 | L3MBTL1 (0.62) | KMT2AMEN1MAPTNR1I2LMNA | |
| SCHEMBL2834843 | 0.66 | POLB (0.48) | POLBKMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948601-A1 | FAB I INHIBITOR AND PROCESS FOR PREPARING SAME | Crystalgenomics, Inc. (KR) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007043835-A1 | FAB I INHIBITOR AND PROCESS FOR PREPARING SAME | CRYSTALGENOMICS, INC. (KR) | 2007-04-19 | — | — | WO | disclosed |