Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.31 |
| ▸ | STK17B | O94768 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592749 | 0.78 | POLB (0.47) | S1PR2S1PR1S1PR3LPAR2LMNA | |
| SCHEMBL2179508 | 0.70 | BACE1 (0.35) | — | |
| SCHEMBL600960 | 0.63 | GPR84 (0.39) | LMNA | |
| SCHEMBL10755910 | 0.59 | KMT2A (0.49) | LMNA | |
| SCHEMBL19518041 | 0.58 | MEN1 (0.49) | LMNA | |
| SCHEMBL13975420 | 0.57 | XDH (0.44) | — | |
| SCHEMBL24690529 | 0.57 | TSHR (0.48) | LMNA | |
| SCHEMBL9719833 | 0.56 | ALDH1A1 (0.55) | SMN1; SMN2 | |
| SCHEMBL16602199 | 0.56 | CYP19A1 (0.47) | LMNASMN1; SMN2 | |
| SCHEMBL8840458 | 0.56 | XDH (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948601-A1 | FAB I INHIBITOR AND PROCESS FOR PREPARING SAME | Crystalgenomics, Inc. (KR) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007043835-A1 | FAB I INHIBITOR AND PROCESS FOR PREPARING SAME | CRYSTALGENOMICS, INC. (KR) | 2007-04-19 | — | — | WO | disclosed |