SCHEMBL4592875

SCHEMBL4592875

Nc1c(C(=O)c2cccc(-c3ccccc3)c2N)cccc1-c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.57
HNF4A P41235 1/20 0.53
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MAPT P10636 3/20 0.46
HTT P42858 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CHRNB2 P17787 3/20 0.46
CHRNB4 P30926 3/20 0.46
CHRNA3 P32297 3/20 0.46
CHRNA4 P43681 3/20 0.46
ALDH1A1 P00352 2/20 0.45
HSD17B10 Q99714 1/20 0.45
FABP3 P05413 1/20 0.44
FABP4 P15090 1/20 0.44
FABP5 Q01469 1/20 0.44
MAPK13 O15264 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL758071 0.88 HNF4A (0.63) BCAT2HNF4AMEN1KMT2ASMN1; SMN2
SCHEMBL3433069 0.86 BCAT2 (0.71) BCAT2HNF4AMEN1KMT2ASMN1; SMN2
SCHEMBL7502280 0.85 HNF4A (0.56) BCAT2HNF4AMEN1KMT2ASMN1; SMN2
SCHEMBL27775809 0.85 BCAT2 (0.55) BCAT2HNF4AMEN1KMT2ASMN1; SMN2
SCHEMBL3792131 0.85 BCAT2 (0.53) BCAT2HNF4AMEN1KMT2ASMN1; SMN2
SCHEMBL8802017 0.83 BCAT2 (0.51) BCAT2HNF4AMEN1KMT2ASMN1; SMN2
SCHEMBL28147858 0.82 MAPT (0.54) BCAT2HNF4AMEN1KMT2AMAPT
SCHEMBL27471401 0.82 HDAC7 (0.51) BCAT2HNF4ASMN1; SMN2HTTCHRNB2
SCHEMBL28510624 0.82 BCAT2 (0.50) BCAT2HNF4AMEN1KMT2ASMN1; SMN2
SCHEMBL17744826 0.82 G6PD (0.59) BCAT2HNF4AMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0607976-B1 Alignment treating agent for liquid crystal cell NISSAN CHEMICAL IND LTD (JP) 2002-11-13 EP claimed
US-12590208-B2 Thermoplastic resin foam, thermoplastic resin foam sheet, fiber-reinforced resin composite, method for manufacturing thermoplastic resin foam, thermoplastic resin foam molded article, method for manufacturing thermoplastic resin foam molded article, and foamed resin composite SEKISUI KASEI CO., LTD. (JP) 2026-03-31 US disclosed
EP-4190533-B1 THERMOPLASTIC RESIN FOAM, THERMOPLASTIC RESIN FOAM SHEET, FIBER-REINFORCED RESIN COMPOSITE, METHOD FOR MANUFACTURING THERMOPLASTIC RESIN FOAM, THERMOPLASTIC RESIN FOAM MOLDED ARTICLE, METHOD FOR MANUFACTURING THERMOPLASTIC RESIN FOAM MOLDED ARTICLE, AND FOAMED RESIN COMPOSITE SEKISUI KASEI CO LTD (JP) 2025-10-01 EP disclosed
WO-2023238958-A1 FOAMED THERMOPLASTIC RESIN PARTICLES, MOLDED BODY OF FOAMED THERMOPLASTIC RESIN PARTICLES, FOAMED RESIN COMPOSITE, METHOD FOR PRODUCING FOAMED THERMOPLASTIC RESIN PARTICLES, AND METHOD FOR PRODUCING MOLDED BODY OF FOAMED THERMOPLASTIC RESIN PARTICLES 積水化成品工業株式会社 2023-12-14 WO disclosed
US-20230295420-A1 THERMOPLASTIC RESIN FOAM, THERMOPLASTIC RESIN FOAM SHEET, FIBER-REINFORCED RESIN COMPOSITE, METHOD FOR MANUFACTURING THERMOPLASTIC RESIN FOAM, THERMOPLASTIC RESIN FOAM MOLDED ARTICLE, METHOD FOR MANUFACTURING THERMOPLASTIC RESIN FOAM MOLDED ARTICLE, AND FOAMED RESIN COMPOSITE SEKISUI KASEI CO., LTD. (JP) 2023-09-21 US disclosed
EP-4190533-A1 THERMOPLASTIC RESIN FOAM, THERMOPLASTIC RESIN FOAM SHEET, FIBER-REINFORCED RESIN COMPOSITE, METHOD FOR MANUFACTURING THERMOPLASTIC RESIN FOAM, THERMOPLASTIC RESIN FOAM MOLDED ARTICLE, METHOD FOR MANUFACTURING THERMOPLASTIC RESIN FOAM MOLDED ARTICLE, AND FOAMED RESIN COMPOSITE Sekisui Kasei Co., Ltd. (JP) 2023-06-07 EP disclosed
US-7459217-B2 Flame retardant polyester film and processed product including the same TORAY INDUSTRIES, INC. (JP) 2008-12-02 US disclosed
EP-1142936-B1 BIAXIALLY ORIENTED FILM AND MAGNETIC RECORDING MEDIUM TORAY INDUSTRIES (JP) 2008-01-02 EP disclosed
EP-1441001-B1 Flame-retardant polyester film and processed product including the same TORAY INDUSTRIES (JP) 2007-11-28 EP disclosed
US-7022396-B1 Biaxially oriented film having specified micro protrusions TORAY INDUSTRIES, INC. (JP) 2006-04-04 US disclosed
EP-1215043-B1 Polyester film and magnetic recording medium using the same TORAY INDUSTRIES (JP) 2006-03-22 EP disclosed
US-6783889-B2 FOR USE IN DIGITAL RECORDING TYPE CASSETTE TAPE; QUALITY; FOR HIGH-DENSITY RECORDING, DIMENSIONAL STABILITY TORAY INDUSTRIES, INC. (JP) 2004-08-31 US disclosed
US-20040161620-A1 Flame retardant polyester film and processed product including the same TORAY INDUSTRIES, INC. (JP) 2004-08-19 US disclosed
EP-1441001-A2 Flame-retardant polyester film and processed product including the same TORAY INDUSTRIES, INC. (JP) 2004-07-28 EP disclosed
US-20020114977-A1 Polyester film and magnetic recording medium using the same TORAY INDUSTRIES, INC. (JP) 2002-08-22 US disclosed
EP-1215043-A1 Polyester film and magnetic recording medium using the same TORAY INDUSTRIES, INC. (JP) 2002-06-19 EP disclosed
EP-1142936-A1 BIAXIALLY ORIENTED FILM AND MAGNETIC RECORDING MEDIUM TORAY INDUSTRIES, INC. (JP) 2001-10-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590208-B2 Thermoplastic resin foam, thermoplastic resin foam sheet, fiber-reinforced resin composite, method for manufacturing thermoplastic resin foam, thermoplastic resin foam molded article, method for manufacturing thermoplastic resin foam molded article, and foamed resin composite TAF9, TAF1, TAF11 BCAT2 3461/4885HNF4A 2664/4885MEN1 3106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.