SCHEMBL27775809

SCHEMBL27775809

Nc1cccc(C(=O)c2ccccc2-c2ccccc2)c1N

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.55
MAPK13 O15264 1/20 0.54
MAPK12 P53778 1/20 0.54
MAPK11 Q15759 1/20 0.54
MAPK14 Q16539 1/20 0.54
ALDH1A1 P00352 2/20 0.48
HSD17B10 Q99714 1/20 0.48
HNF4A P41235 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MAPT P10636 2/20 0.46
GAA P10253 1/20 0.46
CHRNB2 P17787 3/20 0.45
CHRNB4 P30926 3/20 0.45
CHRNA3 P32297 3/20 0.45
CHRNA4 P43681 3/20 0.45
TSHR P16473 1/20 0.42
RECQL P46063 1/20 0.42
HTT P42858 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27783784 0.87 MAPT (0.60) BCAT2MAPK13MAPK12MAPK11MAPK14
SCHEMBL7502280 0.86 HNF4A (0.56) BCAT2MAPK13MAPK12MAPK11MAPK14
SCHEMBL4592875 0.85 BCAT2 (0.57) BCAT2MAPK13MAPK12MAPK11MAPK14
SCHEMBL8802017 0.83 BCAT2 (0.51) BCAT2MAPK13MAPK12MAPK11MAPK14
SCHEMBL5549354 0.83 BCAT2 (0.68) BCAT2MAPK13MAPK12MAPK11MAPK14
SCHEMBL686612 0.83 MAPT (0.50) ALDH1A1HSD17B10MAPTGAATSHR
SCHEMBL3289236 0.81 MAPT (0.61) ALDH1A1HSD17B10MAPTGAATSHR
SCHEMBL7502273 0.80 HNF4A (0.53) BCAT2MAPK13MAPK12MAPK11MAPK14
Bicarbonate SCHEMBL20565740 0.80 ALDH1A1 (0.58) BCAT2MAPK13MAPK12MAPK11MAPK14
Bicarbonate SCHEMBL626712 0.80 ALDH1A1 (0.58) BCAT2MAPK13MAPK12MAPK11MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101684202-B Azo pigment, electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KK 2013-07-17 CN disclosed
CN-101684202-A Azo pigment, electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KK 2010-03-31 CN disclosed