Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30788894 | 0.91 | CASP1 (0.51) | TACR1ALDH1A1CA12CA1CA2 | |
| SCHEMBL1290959 | 0.86 | CTSL (0.52) | ALDH1A1CASP1CTSLCTSSCTSK | |
| SCHEMBL1290957 | 0.86 | CTSL (0.52) | ALDH1A1CASP1CTSLCTSSCTSK | |
| SCHEMBL8346395 | 0.83 | SIRT2 (0.52) | TACR1CASP1CTSLCTSSCTSK | |
| SCHEMBL4212334 | 0.81 | TACR1 (0.49) | TACR1ALDH1A1POLBACEMBTPS1 | |
| SCHEMBL7598622 | 0.79 | TACR1 (0.47) | TACR1ALDH1A1CA12CA1CA2 | |
| SCHEMBL24111516 | 0.78 | TACR1 (0.66) | TACR1ALDH1A1POLBACEMBTPS1 | |
| SCHEMBL2102910 | 0.77 | CASP1 (0.52) | TACR1ALDH1A1CA12CA1CA2 | |
| SCHEMBL28709501 | 0.76 | ALDH1A1 (0.53) | TACR1ALDH1A1POLBCASP1ACE | |
| SCHEMBL11432342 | 0.74 | CTSK (0.61) | ALDH1A1CTSLCTSSCTSKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122661-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS (DE) | 2006-11-23 | — | — | WO | disclosed |