Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816364 | 0.90 | PTPRB (0.40) | PRKCAMEN1NR1I2LMNACHRM2 | |
| SCHEMBL7648225 | 0.89 | CYP2A6 (0.43) | MEN1LMNAMAPTHTR2BKMT2A | |
| SCHEMBL9603526 | 0.86 | HTR1B (0.48) | CHRM2KCNA3ELANE | |
| SCHEMBL7399139 | 0.83 | DDB1 (0.46) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL9596671 | 0.82 | KCNA3 (0.42) | KCNA3ELANEKDM4EALDH1A1GAA | |
| SCHEMBL918577 | 0.81 | KCNA3 (0.63) | PRKCAMEN1NR1I2LMNACHRM2 | |
| Water SCHEMBL8678456 | 0.81 | DDB1 (0.45) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL28110463 | 0.80 | ELANE (0.38) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11064554 | 0.80 | KCNA3 (0.40) | KCNA3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL10776993 | 0.80 | CDK2 (0.43) | MEN1KMT2APDE5AKCNA3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922359-A1 | A DEGRADABLE POLYMER ARTICLE | Ciba Holding Inc. (CH) | 2008-05-21 | — | — | EP | disclosed |
| WO-2007028731-A1 | A DEGRADABLE POLYMER ARTICLE | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-03-15 | — | — | WO | disclosed |