Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 4/20 | 0.38 |
| ▸ | PRKCA | P17252 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593117 | 0.90 | PRKCA (0.45) | KCNA3ELANEPRKCAHPGDPDE5A | |
| SCHEMBL7648225 | 0.82 | CYP2A6 (0.43) | KCNA3ELANEHPGDPDE5APDE4A | |
| SCHEMBL9603526 | 0.80 | HTR1B (0.48) | KCNA3ELANECHRM2 | |
| SCHEMBL7399139 | 0.76 | DDB1 (0.46) | HPGDMEN1MAPTKMT2A | |
| SCHEMBL9596671 | 0.76 | KCNA3 (0.42) | MAOAMAOBKCNA3ELANEHPGD | |
| Water SCHEMBL8678456 | 0.75 | DDB1 (0.45) | HPGDMEN1MAPTKMT2A | |
| SCHEMBL10776993 | 0.74 | CDK2 (0.43) | KCNA3HPGDPDE5AMEN1KMT2A | |
| SCHEMBL11064554 | 0.74 | KCNA3 (0.40) | MAOAMAOBKCNA3HPGD | |
| SCHEMBL17154508 | 0.73 | KCNA3 (0.40) | KCNA3HPGDLMNACHRM2 | |
| SCHEMBL17154500 | 0.73 | HTR7 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997010247-A1 | CLAVULANIC ACID DERIVATIVES FOR TREATING ATHEROSCLEROSIS | SMITHKLINE BEECHAM P.L.C. (GB) | 1997-03-20 | — | — | WO | disclosed |