Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 9/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593117 | 0.86 | PRKCA (0.45) | CHRM2ELANEKCNA3 | |
| SCHEMBL7648225 | 0.84 | CYP2A6 (0.43) | ELANEKCNA3 | |
| SCHEMBL17154500 | 0.81 | HTR7 (0.51) | HTR1BFLT3 | |
| SCHEMBL8816364 | 0.80 | PTPRB (0.40) | CHRM2ELANEKCNA3 | |
| SCHEMBL11064554 | 0.79 | KCNA3 (0.40) | KCNA3 | |
| SCHEMBL7399139 | 0.78 | DDB1 (0.46) | — | |
| SCHEMBL9596671 | 0.77 | KCNA3 (0.42) | FLT3ELANEKCNA3 | |
| Water SCHEMBL8678456 | 0.77 | DDB1 (0.45) | — | |
| SCHEMBL10776993 | 0.76 | CDK2 (0.43) | KCNA3 | |
| SCHEMBL7795729 | 0.76 | ELANE (0.50) | HTR1BHTR1DFLT3ELANEKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192799-A | Coumaran group containing amine compounds and their acid addition salts and quaternary ammonium salts and the use thereof as anti arrhythmic agents and as psychotropic agents | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-09 | — | — | US | disclosed |
| EP-0424525-A1 | NOVEL AMINES AND THEIR USE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |