Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.34 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.34 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.34 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 8/20 | 0.33 |
| ▸ | CA2 | P00918 | 8/20 | 0.33 |
| ▸ | CA9 | Q16790 | 7/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593117 | 0.80 | PRKCA (0.45) | ELANEPDE5APDE4APDE4BPDE4C | |
| SCHEMBL27611345 | 0.80 | ALPL (0.41) | ELANEPOLMPOLKPOLLPOLH | |
| SCHEMBL27593199 | 0.80 | ALPL (0.41) | ELANEPOLMPOLKPOLLPOLH | |
| SCHEMBL1027363 | 0.72 | KDM4E (0.43) | CASP3 | |
| SCHEMBL8816364 | 0.71 | PTPRB (0.40) | ELANEPDE5APDE4APDE4BPDE4C | |
| SCHEMBL7648225 | 0.70 | CYP2A6 (0.43) | ELANEPDE5APDE4APDE4BPDE4C | |
| SCHEMBL10726425 | 0.69 | NR1H2 (0.40) | ELANE | |
| SCHEMBL31197390 | 0.69 | NR1H2 (0.37) | ELANEPOLMPOLKPOLLPOLH | |
| SCHEMBL9603526 | 0.69 | HTR1B (0.48) | ELANE | |
| SCHEMBL5077444 | 0.68 | ALDH1A1 (0.61) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570978-B | Rubber composition for tire and pneumatic tire | 住友橡胶工业株式会社 | 2016-12-28 | — | — | CN | disclosed |