Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL4593432 | 0.75 | TSHR (0.38) | — | |
| SCHEMBL4470018 | 0.70 | KCNN4 (0.41) | KCNN4KCNE1KCNQ1MLNRNR1I2 | |
| Chlorobenzene SCHEMBL4593782 | 0.69 | TSHR (0.35) | — | |
| Bromobenzene SCHEMBL4593844 | 0.68 | ALDH1A1 (0.34) | — | |
| SCHEMBL11862432 | 0.68 | KCNN4 (0.51) | KCNN4KCNE1KCNQ1MLNRNR1I2 | |
| SCHEMBL11861229 | 0.67 | KCNN4 (0.48) | KCNN4KCNE1KCNQ1MLNRNR1I2 | |
| Diphenylether SCHEMBL4592882 | 0.67 | LTA4H (0.36) | — | |
| Toluene SCHEMBL4592876 | 0.65 | KIF11 (0.35) | KCNH2 | |
| SCHEMBL198144 | 0.64 | KCNN4 (0.32) | KCNN4 | |
| SCHEMBL11865400 | 0.64 | KIF11 (0.41) | KCNN4KCNE1KCNQ1MLNRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937257-A1 | NOVEL ANTIBIOTICS COMPRISING BIS(1-ARYL-5-TETRAZ0LYL)METHANE DERIVATIVES | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) | 2008-07-02 | — | — | EP | claimed |
| WO-2007037685-A1 | NOVEL ANTIBIOTICS COMPRISING BIS(1-ARYL-5-TETRAZ0LYL)METHANE DERIVATIVES | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2007-04-05 | — | — | WO | claimed |