Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28342821 | 0.84 | CYP3A4 (0.42) | TSHRHTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL2089381 | 0.79 | ACHE (0.41) | TSHRTP53CYP3A4ALDH1A1LMNA | |
| SCHEMBL4593314 | 0.79 | TTR (0.49) | TSHRTP53LMNAHPGDKMT2A | |
| SCHEMBL29068865 | 0.78 | TRPV4 (0.49) | TSHRCYP1A2KDM4ETP53CYP2C19 | |
| SCHEMBL13651759 | 0.78 | TRPV4 (0.49) | TSHRCYP1A2KDM4ETP53CYP2C19 | |
| SCHEMBL28746894 | 0.78 | TTR (0.47) | TSHRTP53LMNAHPGDKMT2A | |
| SCHEMBL27870121 | 0.77 | TSHR (0.42) | TSHRHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL11817371 | 0.77 | MEN1 (0.44) | KDM4ETP53ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL807773 | 0.76 | SLC6A2 (0.59) | TSHRHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL18348326 | 0.76 | KDM4E (0.42) | TSHRKDM4ETP53ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3991042-A | Basic azo dyestuffs containing a benzthiazole and a tetrahydroquinoline nucleus | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-09 | — | — | US | claimed |
| US-3948877-A | POLYACRYLONITRILE, ACID MODIFIED POLYESTERS OR POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-06 | — | — | US | claimed |
| US-20230033573-A1 | CERTAIN (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE 1 INHIBITORS | BIOPHARMA CREDIT PLC (GB) | 2023-02-02 | — | — | US | disclosed |
| CN-102924237-A | Method for preparing o-cresol and 2,6-dimethyl phenol in mode of reducing unit consumption of methanol | BLUESTAR NEW CHEMICAL MATERIALS CO LTD | 2013-02-13 | — | — | CN | disclosed |
| US-20110306671-A1 | AMIDE DERIVATIVES OF ETHACRYNIC ACID | The Regents of the The University of California (US) | 2011-12-15 | — | — | US | disclosed |
| CN-1258521-C | Method for preparing 2 metho 4 chlorine artificial half antigen, artificial antigen, specific antibody and application | UNIV ZHEJIANG (CN) | 2006-06-07 | — | — | CN | disclosed |
| US-4424363-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1984-01-03 | — | — | US | disclosed |
| US-4354031-A | HERBICIDES | BASF ATIENGESELLSCHAFT (DE) | 1982-10-12 | — | — | US | disclosed |
| US-4316039-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | disclosed |
| US-4260775-A | Substituted 3-aminopyrazoles | BASF AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4259350-A | PROTECTING DEGRADABLE ORGANIC MATERIAL FROM FUNGAL OR INSECT ATTACK | SANKYO COMPANY LIMITED (JP) | 1981-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306671-A1 | AMIDE DERIVATIVES OF ETHACRYNIC ACID | EPX, TNF, NFKBIA | TSHR 3233/4885HTR2A 1734/4885HTR2C 3141/4885 |
| US-20230033573-A1 | CERTAIN (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE 1 INHIBITORS | DPP4, DPP7, DPEP1 | TSHR 4207/4885HTR2A 3234/4885HTR2C 2679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.