Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 5/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593339 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAEGFRERBB2HTT | |
| SCHEMBL8998078 | 0.83 | CYP2B6 (0.44) | ALDH1A1LMNAEGFRERBB2HTT | |
| SCHEMBL16774399 | 0.79 | DHODH (0.45) | ALDH1A1LMNAEGFRERBB2HTT | |
| SCHEMBL16774378 | 0.79 | PGK1 (0.41) | LMNAEGFRERBB2CYP2B6PGK1 | |
| SCHEMBL17197232 | 0.79 | LMNA (0.41) | ALDH1A1LMNAEGFRERBB2CYP2B6 | |
| SCHEMBL8982258 | 0.78 | NPC1 (0.46) | ALDH1A1LMNAEGFRERBB2CYP2B6 | |
| SCHEMBL16774525 | 0.76 | PGK1 (0.39) | LMNAEGFRERBB2CYP2B6PGK1 | |
| SCHEMBL7477262 | 0.75 | PGK1 (0.43) | ALDH1A1LMNAEGFRERBB2HTT | |
| SCHEMBL19048819 | 0.74 | CYP2B6 (0.36) | LMNAEGFRERBB2HTTCYP2B6 | |
| SCHEMBL16774328 | 0.74 | LMNA (0.38) | LMNAEGFRERBB2HTTCYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8212050-B2 | Amidine compounds and herbicides | NIPPON SODA CO., LTD. (JP) | 2012-07-03 | — | — | US | disclosed |
| US-20110301355-A1 | Amidine compounds and herbicides | NIPPON SODA CO., LTD. (JP) | 2011-12-08 | — | — | US | disclosed |
| EP-1911350-A1 | AMIDINE COMPOUND AND HERBICIDE | NIPPON SODA CO., LTD. (JP) | 2008-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301355-A1 | Amidine compounds and herbicides | DDT, GATD3, PAM | ALDH1A1 1998/4885LMNA 1418/4885EGFR 3184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.