SCHEMBL4593438

SCHEMBL4593438

N=C(N)c1ccccc1S(N)(=O)=O

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 14/20 0.56
CA2 P00918 14/20 0.56
CA9 Q16790 11/20 0.56
CA5A P35218 3/20 0.55
CA6 P23280 3/20 0.48
CA4 P22748 2/20 0.48
CA12 O43570 2/20 0.48
CA7 P43166 2/20 0.48
CA5B Q9Y2D0 2/20 0.48
CYP2C9 P11712 1/20 0.48
CA14 Q9ULX7 1/20 0.48
LDHA P00338 1/20 0.42
CDK2 P24941 1/20 0.42
F10 P00742 2/20 0.41
PRSS1 P07477 2/20 0.41
PRSS2 P07478 2/20 0.41
PRSS3 P35030 2/20 0.41
F2 P00734 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7562109 0.83 TTR (0.41) CA1CA2CA9CA5AF10
SCHEMBL4593659 0.82 CDK2 (0.47) CA1CA2CA9CA5ACA6
SCHEMBL3555054 0.82 BCAT2 (0.50) CA1CA2CA9CA5AF10
SCHEMBL353392 0.81 CA1 (0.63) CA1CA2CA9CA5ACA6
Bromide SCHEMBL7107769 0.79 CA1 (0.61) CA1CA2CA9CA5ACA6
SCHEMBL1807636 0.79 CA2 (0.61) CA1CA2CA9CA5ACA6
SCHEMBL4617916 0.79 CA1 (0.62) CA1CA2CA9CA5ACA12
SCHEMBL353738 0.77 CA1 (0.63) CA1CA2CA9CA5ACA6
SCHEMBL31191409 0.77 CA1 (0.63) CA1CA2CA9CA5ACA6
SCHEMBL7837493 0.76 CA1 (0.53) CA1CA2CA9CA5ACA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3607084-A1 A METHOD FOR TESTING ANTIMICROBIAL SUSCEPTIBILITY The University Of Western Australia (AU) 2020-02-12 EP disclosed
WO-2018184073-A1 A METHOD FOR TESTING ANTIMICROBIAL SUSCEPTIBILITY THE UNIVERSITY OF WESTERN AUSTRALIA (AU) 2018-10-11 WO disclosed
EP-1934214-A1 OXADIAZOLYL PYRAZOLO-PYRIMIDINES AS MGLUR2 ANTAGONISTS F.HOFFMANN-LA ROCHE AG (CH) 2008-06-25 EP disclosed
WO-2007039439-A1 OXADIAZOLYL PYRAZOLO-PYRIMIDINES AS MGLUR2 ANTAGONISTS F.HOFFMANN-LA ROCHE AG (CH) 2007-04-12 WO disclosed