Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15301603 | 0.76 | TSHR (0.55) | ALDH1A1LMNATSHRRAB9AHPGD | |
| SCHEMBL29666364 | 0.76 | RAB9A (0.70) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL7407182 | 0.76 | SMN1; SMN2 (0.53) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL4601158 | 0.76 | AAK1 (0.44) | RAB9ANPC1HTTEGFR | |
| SCHEMBL9407130 | 0.75 | L3MBTL1 (0.62) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL2538042 | 0.75 | CYP1A2 (0.53) | ALDH1A1NPSR1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL3164480 | 0.74 | CA1 (0.44) | ALDH1A1TSHRRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8710366 | 0.74 | RAB9A (0.52) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL16696407 | 0.74 | RAB9A (0.47) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL16696408 | 0.74 | RAB9A (0.74) | L3MBTL1ALDH1A1LMNATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896396-A1 | ANTHRANILIC ACID DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006134040-A1 | ANTHRANILIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-21 | — | — | WO | disclosed |