Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 7/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484220 | 0.93 | SSTR5 (0.44) | SSTR5SSTR1HRH1HDAC6KCNH2 | |
| SCHEMBL4593843 | 0.92 | SSTR5 (0.43) | SSTR5SSTR1HRH1HDAC6KCNH2 | |
| SCHEMBL4594363 | 0.90 | SSTR5 (0.41) | SSTR5SSTR1HRH1HDAC6HPSE | |
| SCHEMBL4593945 | 0.89 | SSTR5 (0.41) | SSTR5SSTR1HRH1HDAC6KCNH2 | |
| SCHEMBL4593544 | 0.88 | SSTR5 (0.46) | SSTR5SSTR1HDAC6HPSEKCNH2 | |
| SCHEMBL4593872 | 0.88 | SSTR5 (0.54) | SSTR5SSTR1HDAC6HPSEKCNH2 | |
| SCHEMBL4593393 | 0.87 | SSTR5 (0.42) | SSTR5SSTR1HRH1KCNH2NPC1 | |
| SCHEMBL4594029 | 0.86 | SSTR5 (0.41) | SSTR5SSTR1HRH1KCNH2MAPT | |
| SCHEMBL5488609 | 0.86 | SSTR5 (0.41) | SSTR5HRH1 | |
| SCHEMBL1378217 | 0.85 | SSTR5 (0.49) | SSTR5SSTR1HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924579-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-28 | — | — | EP | claimed |
| WO-2007025897-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-08 | — | — | WO | claimed |
| EP-1924579-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007025897-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-08 | — | — | WO | disclosed |