Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29404409 | 0.90 | CES2 (0.38) | CES2CES1CYP2C9MEN1KMT2A | |
| SCHEMBL3341200 | 0.90 | CES2 (0.38) | CES2CES1CYP2C9MEN1KMT2A | |
| SCHEMBL714064 | 0.88 | MEN1 (0.37) | CES2CES1CYP2C9MEN1KMT2A | |
| SCHEMBL29405294 | 0.88 | MEN1 (0.37) | CES2CES1CYP2C9MEN1KMT2A | |
| SCHEMBL3646838 | 0.88 | MEN1 (0.37) | CES2CES1CYP2C9MEN1KMT2A | |
| SCHEMBL20262187 | 0.84 | MEN1 (0.35) | CES2CES1CYP2C9MEN1KMT2A | |
| SCHEMBL712618 | 0.82 | MEN1 (0.34) | CYP2C9MEN1KMT2ACYP1A2HSD17B10 | |
| SCHEMBL8576244 | 0.82 | MEN1 (0.34) | CYP2C9MEN1KMT2ACYP1A2HSD17B10 | |
| SCHEMBL4594690 | 0.80 | MEN1 (0.33) | CYP2C9MEN1KMT2ACYP1A2HPGD | |
| SCHEMBL22766208 | 0.79 | MEN1 (0.37) | CES2CES1CYP2C9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217827-B2 | Halogen-containing aromatic compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-05-15 | — | — | US | claimed |
| US-20050090691-A1 | Halogen-containing aromatic compound | NIPPON SHOKUBAI CO., LTD., A JAPAN CORPORATION | 2005-04-28 | — | — | US | claimed |
| US-20030018204-A1 | Halogen-containing aromatic compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2003-01-23 | — | — | US | claimed |
| EP-1462436-B1 | Halogen-containing aromatic compound | NIPPON CATALYTIC CHEM IND (JP) | 2008-01-02 | — | — | EP | disclosed |
| US-7217827-B2 | Halogen-containing aromatic compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-05-15 | — | — | US | disclosed |
| US-6916959-B2 | Halogen-containing aromatic compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |
| US-20050090691-A1 | Halogen-containing aromatic compound | NIPPON SHOKUBAI CO., LTD., A JAPAN CORPORATION | 2005-04-28 | — | — | US | disclosed |
| EP-1462436-A1 | Halogen-containing aromatic compound | Nippon Shokubai Co., Ltd. (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-20030018204-A1 | Halogen-containing aromatic compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2003-01-23 | — | — | US | disclosed |
| EP-1256564-A1 | Halogen-containing aromatic compound | Nippon Shokubai Co., Ltd. (JP) | 2002-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090691-A1 | Halogen-containing aromatic compound | TYR, AFF4, DDT | CES2 2043/4885CES1 4620/4885CYP2C9 414/4885 |
| US-20030018204-A1 | Halogen-containing aromatic compound | TYR, AFF4, DDT | CES2 2043/4885CES1 4620/4885CYP2C9 414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.