Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 8/20 | 0.33 |
| ▸ | PPARA | Q07869 | 8/20 | 0.33 |
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594418 | 0.89 | PPARD (0.37) | SLC6A2SLC6A4SLC6A3PPARDPPARA | |
| SCHEMBL4594500 | 0.87 | PPARD (0.35) | SLC6A2SLC6A4SLC6A3PPARDPPARA | |
| SCHEMBL4594214 | 0.85 | MAPK1 (0.36) | MAPK1SLC6A2SLC6A4SLC6A3PPARD | |
| SCHEMBL4593880 | 0.85 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3PPARDPPARA | |
| SCHEMBL4593394 | 0.84 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3PPARDPPARA | |
| SCHEMBL4593207 | 0.83 | SSTR5 (0.36) | SLC6A2SLC6A4SLC6A3PPARDPPARA | |
| SCHEMBL4594412 | 0.82 | HDAC6 (0.38) | PPARDPPARAPPARGHTR2ASSTR5 | |
| SCHEMBL4594566 | 0.81 | HTR2A (0.35) | PPARDPPARAPPARGHTR2ASSTR5 | |
| SCHEMBL4594697 | 0.81 | GAA (0.41) | SLC6A2SLC6A4SLC6A3PPARDPPARA | |
| SCHEMBL4593462 | 0.80 | RAB9A (0.40) | HTR2ASSTR5MBTPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924579-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-28 | — | — | EP | claimed |
| WO-2007025897-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-08 | — | — | WO | claimed |
| EP-1924579-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007025897-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-08 | — | — | WO | disclosed |