Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10630163 | 0.81 | GSR (0.50) | GSRGABRA1GABRB1GABRB2GABRA5 | |
| SCHEMBL6414244 | 0.79 | TYR (0.46) | CA1CA2MAPTTYRLMNA | |
| SCHEMBL13057520 | 0.79 | GSR (0.57) | GSRGABRA1GABRB1GABRB2GABRA5 | |
| SCHEMBL11578331 | 0.78 | GSR (0.47) | GSRGABRA1GABRB1GABRB2GABRA5 | |
| SCHEMBL4594369 | 0.78 | GSR (0.55) | GSRGABRA1GABRB1GABRB2GABRA5 | |
| SCHEMBL4595014 | 0.78 | GSR (0.55) | GSRGABRA1GABRB1GABRB2GABRA5 | |
| SCHEMBL27928023 | 0.78 | PTGS1 (0.48) | CA1CA2MAPTTYRLMNA | |
| SCHEMBL2467528 | 0.76 | GSR (0.63) | GSRGABRA1GABRB1GABRB2GABRA5 | |
| SCHEMBL200138 | 0.76 | GABRA1 (0.60) | GSRGABRA1GABRB1GABRB2GABRA5 | |
| SCHEMBL11810825 | 0.76 | GSR (0.53) | GSRGABRA1GABRB1GABRB2GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050277700-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | MCNEIL-PPC, INC | 2005-12-15 | — | — | US | disclosed |
| US-20040199028-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | MCNEIL-PPC, INC | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277700-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | HDHD5, TYR, NONO | GSR 1658/4885GABRA1 4282/4885GABRB1 4487/4885 |
| US-20040199028-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | HDHD5, TYR, NONO | GSR 1658/4885GABRA1 4282/4885GABRB1 4487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.