SCHEMBL4595138

SCHEMBL4595138

O=Cc1cc(Cl)cc(C=O)n1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 5/20 0.42
TERT O14746 5/20 0.40
CCR1 P32246 2/20 0.39
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.36
S1PR4 O95977 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
APP P05067 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
CCR5 P51681 1/20 0.32
CCR8 P51685 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL9637800 0.91 ERN1 (0.37) ERN1TERTCCR1TSHRHSD17B10
SCHEMBL29945725 0.87 ERN1 (0.38) ERN1TERTCCR1TSHRHSD17B10
SCHEMBL1572837 0.87 ERN1 (0.38) ERN1TERTCCR1TSHRHSD17B10
SCHEMBL23580086 0.84 ERN1 (0.35) ERN1TERTCCR1HSD17B10S1PR4
SCHEMBL6551038 0.84 POLB (0.37) ERN1TERTCCR1CYP1A2CYP3A4
SCHEMBL30044498 0.84 ERN1 (0.35) ERN1TERTCCR1HSD17B10S1PR4
SCHEMBL29237183 0.84 ERN1 (0.38) ERN1TERTCCR1HSD17B10S1PR4
SCHEMBL14600867 0.79 ERN1 (0.40) ERN1TERTTSHRS1PR4TDP1
SCHEMBL29955993 0.78 CCR1 (0.39) ERN1TERTCCR1TSHRHSD17B10
SCHEMBL18243729 0.77 TERT (0.32) ERN1TERTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025235427-A1 AU(II) DIMERS AND METHODS OF THEIR USE IN CANCER TREATMENT ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2025-11-13 WO disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-9150837-B2 Polyethylene glycolated superoxide dismutase mimetics GALERA LABS LLC (US) 2015-10-06 US disclosed
US-9150837-B2 Polyethylene glycolated superoxide dismutase mimetics GALERA LABS LLC (US) 2015-10-06 US disclosed
US-9150837-B2 Polyethylene glycolated superoxide dismutase mimetics GALERA LABS LLC (US) 2015-10-06 US disclosed
US-20130287696-A1 POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS GALERA THERAPEUTICS, LLC 2013-10-31 US disclosed
US-20130287696-A1 POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS GALERA THERAPEUTICS, LLC 2013-10-31 US disclosed
US-20130287696-A1 POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS GALERA THERAPEUTICS, LLC 2013-10-31 US disclosed
US-20120301403-A1 POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS GALERA THERAPEUTICS, LLC (US) 2012-11-29 US disclosed
US-20120301403-A1 POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS GALERA THERAPEUTICS, LLC (US) 2012-11-29 US disclosed
US-20040116332-A1 Biopolymers modified with superoxide dismutase mimics PHARMACIA CORPORATION 2004-06-17 US disclosed
US-20040110722-A1 Modified hyaluronic acid polymers PHARMACIA CORPORATION 2004-06-10 US disclosed
EP-1212323-B1 SUBSTITUTED PYRIDINO PENTAAZAMACROCYLE COMPLEXES HAVING SUPEROXIDE DISMUTASE ACTIVITY MONSANTO CO (US) 2004-06-09 EP disclosed
EP-1420022-A1 Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity MONSANTO COMPANY (US) 2004-05-19 EP disclosed
EP-1420022-A1 Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity MONSANTO COMPANY (US) 2004-05-19 EP disclosed
EP-1420019-A1 Substituted pyridino pentaazamacrocyle ligands having superoxide dismutase activity MONSANTO COMPANY (US) 2004-05-19 EP disclosed
WO-2001019823-A9 SUBSTITUTED PYRIDINO PENTAAZAMACROCYLE COMPLEXES HAVING SUPEROXIDE DISMUTASE ACTIVITY MONSANTO CO (US) 2002-09-26 WO disclosed
EP-1212323-A2 SUBSTITUTED PYRIDINO PENTAAZAMACROCYLE COMPLEXES HAVING SUPEROXIDE DISMUTASE ACTIVITY MONSANTO COMPANY (US) 2002-06-12 EP disclosed
US-6214817-B1 NITROGEN MACROCYCLE COMPLEXES WITH MANGANESE AND IRON MONSANTO COMPANY 2001-04-10 US disclosed
WO-2001019823-A2 SUBSTITUTED PYRIDINO PENTAAZAMACROCYLE COMPLEXES HAVING SUPEROXIDE DISMUTASE ACTIVITY MONSANTO COMPANY (US) 2001-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110722-A1 Modified hyaluronic acid polymers CD44, HAO2, HAO1 ERN1 4463/4885TERT 2716/4885CCR1 3338/4885
US-20120301403-A1 POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS SOD1, SOD3, CAT ERN1 1105/4885TERT 593/4885CCR1 3627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.