Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4595596 | 0.86 | AQP1 (0.33) | HTR7HTR2AHTR2C | |
| SCHEMBL4595198 | 0.85 | LMNA (0.39) | LMNAALDH1A1MAPK1 | |
| SCHEMBL4596943 | 0.83 | HTR7 (0.35) | HTR7ALDH1A1MAPK1HTR2AHTR2C | |
| SCHEMBL4224837 | 0.82 | PRKAB2 (0.43) | LMNAHTR7ALDH1A1MAPK1HTR2A | |
| SCHEMBL4762566 | 0.81 | AQP1 (0.42) | HTR7ALDH1A1MAPK1HTR2AHTR2C | |
| SCHEMBL6047945 | 0.80 | GRIA1 (0.35) | HTR7ALDH1A1MAPK1HTR2AHTR2C | |
| SCHEMBL4597398 | 0.79 | LMNA (0.36) | LMNAALDH1A1MAPK1 | |
| SCHEMBL4596599 | 0.79 | GPBAR1 (0.39) | — | |
| SCHEMBL4596811 | 0.79 | HTR7 (0.32) | LMNAHTR7ALDH1A1MAPK1HTR2A | |
| SCHEMBL6047939 | 0.79 | HTR2A (0.40) | HTR7ALDH1A1MAPK1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874750-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth Incoporated (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2007030150-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | WYETH (US) | 2007-03-15 | — | — | WO | disclosed |