SCHEMBL4595239

SCHEMBL4595239

CCCC(c1ccc(C(C)(C)C)cc1O)c1ccc(C(C)(C)C)cc1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 0.51
ALOX15 P16050 2/20 0.51
CYP2C9 P11712 2/20 0.51
CYP2C19 P33261 2/20 0.51
TP53 P04637 1/20 0.51
ALDH1A1 P00352 2/20 0.50
HPGD P15428 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
PKM P14618 1/20 0.42
RECQL P46063 1/20 0.42
KMT2A Q03164 1/20 0.42
RORC P51449 1/20 0.40
CNR1 P21554 2/20 0.40
CNR2 P34972 2/20 0.40
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50921 0.86 RORC (0.51) CYP2D6ALOX15CYP2C9CYP2C19TP53
SCHEMBL5015411 0.82 CYP2C19 (0.54) CYP2D6ALOX15CYP2C9CYP2C19TP53
SCHEMBL9510080 0.81 CYP2C19 (0.49) CYP2D6ALOX15CYP2C9CYP2C19TP53
SCHEMBL4596678 0.78 TYR (0.50) CYP2D6ALOX15CYP2C9CYP2C19TP53
SCHEMBL8443342 0.78 CYP2C19 (0.54) CYP2D6ALOX15CYP2C9CYP2C19TP53
SCHEMBL11329698 0.77 CYP2C19 (0.53) CYP2D6ALOX15CYP2C9CYP2C19TP53
SCHEMBL11699873 0.77 RORC (0.62) CYP2D6ALOX15CYP2C9CYP2C19ALDH1A1
SCHEMBL4595527 0.77 TRPA1 (0.57) CYP2D6ALOX15CYP2C9CYP2C19TP53
SCHEMBL52009 0.76 ALDH1A1 (0.59) CYP2D6ALOX15ALDH1A1HPGDHSD17B10
SCHEMBL5167842 0.76 ALDH1A1 (0.59) CYP2D6ALOX15ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1437231-B1 DEVELOPER FOR THERMAL RECORDING MATERIAL AND THERMAL RECORDING MATERIALS API CORP (JP) 2008-01-09 EP disclosed
US-20040241598-A1 Developer for thermal recording material and thermal recording materials NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2004-12-02 US disclosed
EP-1437231-A1 DEVELOPER FOR THERMAL RECORDING MATERIAL AND THERMAL RECORDING MATERIALS API Corporation (JP) 2004-07-14 EP disclosed