Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339492 | 0.85 | ALOX15 (0.81) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL1532777 | 0.84 | PARP10 (0.65) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL29051537 | 0.83 | ALOX15 (0.65) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL16035699 | 0.83 | ALOX15 (0.65) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL5827387 | 0.83 | ALOX15 (0.65) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL341847 | 0.83 | ALOX15 (0.65) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL5321036 | 0.81 | ALOX15 (0.57) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL459533 | 0.80 | L3MBTL1 (0.66) | ALOX15ALDH1A1SMN1; SMN2FFAR1MAPT | |
| SCHEMBL1965751 | 0.80 | ALOX15 (0.61) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL7832502 | 0.79 | ALOX15 (0.55) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9182385-B2 | Methods for diagnosis, prognosis and methods of treatment | NODALITY, INC. (US) | 2015-11-10 | — | — | US | claimed |
| US-8778620-B2 | Methods for diagnosis, prognosis and methods of treatment | NODALITY, INC. (US) | 2014-07-15 | — | — | US | claimed |
| US-20130130279-A1 | METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT | NODALITY, INC. (US) | 2013-05-23 | — | — | US | claimed |
| US-20120309029-A1 | METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT | NODALITY, INC. (US) | 2012-12-06 | — | — | US | claimed |
| US-8227202-B2 | Methods for diagnosis, prognosis and methods of treatment | NODALITY, INC. (US) | 2012-07-24 | — | — | US | claimed |
| EP-2304436-A1 | METHODS FOR DIAGNOSIS, PROGNOSIS AND TREATMENT | Nodality, Inc. (US) | 2011-04-06 | — | — | EP | claimed |
| EP-2179037-A2 | METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT | Nodality, Inc. (US) | 2010-04-28 | — | — | EP | claimed |
| WO-2010006291-A1 | METHODS FOR DIAGNOSIS, PROGNOSIS AND TREATMENT | NODALITY, INC. (US) | 2010-01-14 | — | — | WO | claimed |
| US-20100009364-A1 | Methods for diagnosis, prognosis and methods of treatment | NODALITY, INC. (US) | 2010-01-14 | — | — | US | claimed |
| US-20090098594-A1 | Methods for diagnosis prognosis and methods of treatment | NODALITY, INC. (US) | 2009-04-16 | — | — | US | claimed |
| WO-2009025847-A2 | METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT | NODALITY, INC. (US) | 2009-02-26 | — | — | WO | claimed |
| US-20170370933-A1 | METHODS AND COMPOSITIONS FOR IMMUNOMODULATION | NODALITY INC (US) | 2017-12-28 | — | — | US | disclosed |
| US-20170370934-A1 | METHODS AND COMPOSITIONS FOR IMMUNOMODULATION | NODALITY INC (US) | 2017-12-28 | — | — | US | disclosed |
| US-20170363633-A1 | METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT | NODALITY INC (US) | 2017-12-21 | — | — | US | disclosed |
| US-20170350911-A1 | HIGH THROUGHPUT FLOW CYTOMETRY SYSTEM AND METHOD | NODALITY INC (US) | 2017-12-07 | — | — | US | disclosed |
| WO-2009134944-A2 | METHODS OF DETERMINING THE HEALTH STATUS OF AN INDIVIDUAL | NODALITY, INC. (US) | 2009-11-05 | — | — | WO | disclosed |
| US-20090269773-A1 | METHODS OF DETERMINING THE HEALTH STATUS OF AN INDIVIDUAL | NODALITY, INC. A DELAWARE CORPORATION | 2009-10-29 | — | — | US | disclosed |
| US-20090269800-A1 | DEVICE AND METHOD FOR PROCESSING CELL SAMPLES | NODALITY, INC. | 2009-10-29 | — | — | US | disclosed |
| US-20090098594-A1 | Methods for diagnosis prognosis and methods of treatment | NODALITY, INC. (US) | 2009-04-16 | — | — | US | disclosed |
| WO-2009025847-A2 | METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT | NODALITY, INC. (US) | 2009-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170370933-A1 | METHODS AND COMPOSITIONS FOR IMMUNOMODULATION | CD47, ICOS, CD74 | ALOX15 685/4885ALDH1A1 1947/4885SMN1; SMN2 1806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.