SCHEMBL4595330

SCHEMBL4595330

CC(C)c1ncc(CCl)cn1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25406537 0.82 APLNR (0.38) APLNR
SCHEMBL2625466 0.78 KDM4E (0.34) APLNR
SCHEMBL485610 0.76 APLNR (0.35) APLNR
SCHEMBL17828156 0.76 APLNR (0.31) APLNR
SCHEMBL2863573 0.76 LOXL2 (0.33) APLNR
SCHEMBL18856278 0.76 GABRA1 (0.36) APLNR
SCHEMBL23869508 0.74 NPC1 (0.38) APLNR
SCHEMBL18929494 0.73 LMNA (0.32) APLNR
SCHEMBL14572015 0.73 GSR (0.42) APLNR
SCHEMBL740241 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100412064-C Malononitrile compounds and its use SUMITOMO CHEMICAL CO (JP) 2008-08-20 CN disclosed
EP-1555259-B1 Malononitrile compounds as pesticides SUMITOMO CHEMICAL CO (JP) 2008-01-02 EP disclosed
CN-1648122-A Malononitrile compounds and its use SUMITOMO CHEMICAL CO (JP) 2005-08-03 CN disclosed
EP-1555259-A1 Malononitrile compounds as pesticides Sumitomo Chemical Company, Limited (JP) 2005-07-20 EP disclosed
US-6297374-B1 Nitroimino-nitromethylene—azole or-azine heterocyclic compounds, insecticidal compositions containing them, and insecticidal methods of using them NIHON BAYER AGROCHEM K.K. (JP) 2001-10-02 US disclosed
US-6022967-A 1-NITRO-2-CARBOXYVINYL- OR 1-NITRO-2-(DIMETHYLAMINO)VINYL-SUBSTITUTED IMIDAZOLIDINES OR TETRAHYDROPYRIMIDINES NIHON BAYER AGROCHEM K.K. (JP) 2000-02-08 US disclosed
US-5750704-A INSECTICIDES NIHON BAYER AGROCHEM K.K. (JP) 1998-05-12 US disclosed
US-5580889-A Insecticidal nitromethyl or niteoimino-heteromethyl-heterocyclics NIHON BAYER AGROCHEM K.K. (JP) 1996-12-03 US disclosed
US-5461167-A 2-chloro-5-chloromethyl thiazole; insecticide NIHON BAYER AGROCHEM K.K. (JP) 1995-10-24 US disclosed
US-5428032-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1995-06-27 US disclosed
US-5298507-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1994-03-29 US disclosed
US-5204360-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1993-04-20 US disclosed
US-5001138-A Insecticides NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) 1991-03-19 US disclosed
US-4845106-A INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-07-04 US disclosed
US-4742060-A 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) 1988-05-03 US disclosed
EP-0192060-A1 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1986-08-27 EP disclosed