Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.69 |
| ▸ | CA2 | P00918 | 6/20 | 0.69 |
| ▸ | CA7 | P43166 | 6/20 | 0.69 |
| ▸ | CA9 | Q16790 | 6/20 | 0.69 |
| ▸ | CA4 | P22748 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MYOC | Q99972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666113 | 0.82 | CA1 (1.00) | CA1CA2CA7CA9CA4 | |
| SCHEMBL4932067 | 0.80 | CA1 (0.76) | CA1CA2CA7CA9CA4 | |
| SCHEMBL14342953 | 0.80 | PTPRC (0.59) | CA1CA2CA9POLBKDM4E | |
| SCHEMBL177892 | 0.79 | CYP3A4 (0.68) | POLBKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL10416104 | 0.76 | ALDH1A1 (0.68) | POLBKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL11689190 | 0.75 | HSPB1 (0.79) | CA1CA2CA9POLBKDM4E | |
| SCHEMBL9183872 | 0.75 | HSPB1 (0.79) | CA1CA2CA9POLBKDM4E | |
| SCHEMBL2011179 | 0.75 | HSPB1 (0.79) | CA1CA2CA9POLBKDM4E | |
| 4,4'-Oxybis(Nitrobenzene) SCHEMBL134332 | 0.75 | HSPB1 (0.79) | CA1CA2CA9POLBKDM4E | |
| SCHEMBL617807 | 0.73 | POLB (0.67) | POLBKDM4EKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1500387-B1 | Use of ninhydrin derivatives for dyeing | OREAL (FR) | 2008-01-09 | — | — | EP | disclosed |
| US-7179306-B2 | Process for dying keratin fibers comprising at least one aryl or aryloxy substitutent-based ninhydrin derivative | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | disclosed |
| US-20050050655-A1 | Process for dyeing keratin fibers comprising at least one aryl or aryloxy substitutent-based ninhydrin derivative | L'OREAL S.A. (FR) | 2005-03-10 | — | — | US | disclosed |
| EP-1500387-A1 | Use of ninhydrin derivatives for dyeing | L'OREAL (FR) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050050655-A1 | Process for dyeing keratin fibers comprising at least one aryl or aryloxy substitutent-based ninhydrin derivative | KRT18, JUP, NISCH | CA1 1947/4885CA2 2607/4885CA7 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.