SCHEMBL4595912

SCHEMBL4595912

CC(S)CCCCCCS

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.35
ENPEP Q07075 1/20 0.32
TRPV1 Q8NER1 1/20 0.31
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25229480 1.00 FOLH1 (0.35) FOLH1ENPEPTRPV1TRPA1
SCHEMBL28913500 1.00 FOLH1 (0.35) FOLH1ENPEPTRPV1TRPA1
SCHEMBL6246334 1.00 FOLH1 (0.35) FOLH1ENPEPTRPV1TRPA1
SCHEMBL6036319 1.00 FOLH1 (0.35) FOLH1ENPEPTRPV1TRPA1
SCHEMBL3499144 0.97
SCHEMBL1445560 0.88
SCHEMBL10949047 0.87 TRPV1 (0.36) TRPV1TRPA1
SCHEMBL1171781 0.87 TRPV1 (0.36) TRPV1TRPA1
SCHEMBL16646714 0.87 TRPV1 (0.36) TRPV1TRPA1
SCHEMBL10945025 0.87 TRPV1 (0.36) TRPV1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1419815-B1 Phosphine compounds, transition metal complexes with the compounds contained as ligands therein, and asymmetric synthesis catalysts containing the complexes TAKASAGO PERFUMERY CO LTD (JP) 2008-01-09 EP claimed
EP-1792898-A1 MOLECULAR CHAPERONE FUNCTION REGULATOR Mitsubishi Pharma Corporation (JP) 2007-06-06 EP claimed
EP-0029311-B1 AMINOALKYL BENZOFURAN DERIVATIVES, THEIR PRODUCTION AND COMPOSITIONS CONTAINING THEM MERCK & CO. INC. (US) 1985-01-23 EP claimed
US-20230124101-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS BEXSON BIOMEDICAL, INC. 2023-04-20 US disclosed
US-11377415-B2 Method for converting N,N-dialkylamide compound into ester compound using complex of fourth-period transition metal as catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 2022-07-05 US disclosed
EP-3760607-A1 METHOD FOR CONVERTING N,N-DIALKYLAMIDE COMPOUND INTO ESTER COMPOUND USING COMPLEX OF FOURTH-PERIOD TRANSITION METAL AS CATALYST Takasago International Corporation (JP) 2021-01-06 EP disclosed
US-20200399200-A1 METHOD FOR CONVERTING N,N-DIALKYLAMIDE COMPOUND INTO ESTER COMPOUND USING COMPLEX OF FOURTH-PERIOD TRANSITION METAL AS CATALYST TAKASAGO INTERNATIONAL CORPORATION (JP) 2020-12-24 US disclosed
EP-1871823-B1 POLYMER CAPSULE AND PROCESS FOR THE PREPARATION THEREOF POSTECH FOUNDATION (KR) 2013-03-27 EP disclosed
US-20080175920-A1 Polymer Capsule and Process For the Preparation Thereof POSTECH FOUNDATION (KR) 2008-07-24 US disclosed
EP-1871823-A1 POLYMER CAPSULE AND PROCESS FOR THE PREPARATION THEREOF Postech Foundation (KR) 2008-01-02 EP disclosed
EP-1792898-A1 MOLECULAR CHAPERONE FUNCTION REGULATOR Mitsubishi Pharma Corporation (JP) 2007-06-06 EP disclosed
WO-2006112673-A1 POLYMER CAPSULE AND PROCESS FOR THE PREPARATION THEREOF POSTECH FOUNDATION (KR) 2006-10-26 WO disclosed
EP-1419815-A1 Phosphine compounds, transition metal complexes with the compounds contained as ligands therein, and asymmetric synthesis catalysts containing the complexes Takasago International Corporation (JP) 2004-05-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11377415-B2 Method for converting N,N-dialkylamide compound into ester compound using complex of fourth-period transition metal as catalyst NEK4, TENT4A, TCF4 FOLH1 3681/4885ENPEP 627/4885TRPV1 3276/4885
US-20200399200-A1 METHOD FOR CONVERTING N,N-DIALKYLAMIDE COMPOUND INTO ESTER COMPOUND USING COMPLEX OF FOURTH-PERIOD TRANSITION METAL AS CATALYST NEK4, TENT4A, TCF4 FOLH1 3681/4885ENPEP 627/4885TRPV1 3276/4885
US-20230124101-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS SLC10A1, SLC5A6, MC2R FOLH1 1739/4885ENPEP 2210/4885TRPV1 762/4885
US-20080175920-A1 Polymer Capsule and Process For the Preparation Thereof GRHPR, BPHL, HPD FOLH1 1540/4885ENPEP 2983/4885TRPV1 4773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.