Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596031 | 0.77 | PARP1 (0.54) | PARP1 | |
| SCHEMBL4596860 | 0.77 | PARP1 (0.36) | PARP1 | |
| SCHEMBL22474535 | 0.74 | HTR1A (0.33) | PARP1 | |
| SCHEMBL22474487 | 0.74 | HTR1A (0.33) | PARP1 | |
| SCHEMBL13993008 | 0.74 | PRKAB2 (0.36) | PARP1 | |
| SCHEMBL11091102 | 0.73 | SMN1; SMN2 (0.35) | PARP1 | |
| SCHEMBL23704398 | 0.73 | CYP19A1 (0.41) | — | |
| SCHEMBL4222577 | 0.73 | KDM4E (0.41) | PARP1 | |
| SCHEMBL5809840 | 0.73 | KDM4E (0.41) | PARP1 | |
| SCHEMBL5791615 | 0.73 | PARP1 (0.33) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874750-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth Incoporated (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2007030150-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | WYETH (US) | 2007-03-15 | — | — | WO | disclosed |