Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | AQP1 | P29972 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047928 | 0.91 | OXTR (0.37) | SIRT2TDP1AQP1PRKAB2PRKAG1 | |
| SCHEMBL6368626 | 0.85 | AQP1 (0.40) | LPAR1LPAR5MEN1KMT2AAQP1 | |
| SCHEMBL4224655 | 0.84 | LPAR1 (0.39) | LPAR1LPAR5MEN1NPC1RAB9A | |
| SCHEMBL4596610 | 0.83 | SIRT2 (0.40) | SIRT2LPAR1LPAR5MEN1NPC1 | |
| SCHEMBL4220403 | 0.81 | AQP1 (0.40) | SIRT2AQP1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4233789 | 0.81 | AQP1 (0.43) | MEN1NPC1RAB9AKMT2AAQP1 | |
| SCHEMBL4595085 | 0.81 | SIRT2 (0.54) | SIRT2AQP1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4596631 | 0.81 | AQP1 (0.57) | SIRT2LPAR1LPAR5MEN1NPC1 | |
| SCHEMBL4596670 | 0.80 | PRKAB2 (0.37) | SIRT2NPC1RAB9AAQP1PRKAB2 | |
| SCHEMBL4229060 | 0.79 | OXTR (0.39) | LPAR1LPAR5MEN1KMT2APRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874750-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth Incoporated (US) | 2008-01-09 | — | — | EP | disclosed |