Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CTSV | O60911 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001887 | 0.88 | EGFR (0.41) | ALDH1A1KDM4ELMNAHPGDTSHR | |
| SCHEMBL6169861 | 0.81 | ATM (0.41) | ALDH1A1KDM4ELMNAHPGDHIF1A | |
| SCHEMBL8978531 | 0.79 | SMN1; SMN2 (0.36) | ALDH1A1KDM4ELMNAHPGDTSHR | |
| SCHEMBL4596761 | 0.78 | MEN1 (0.40) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL7608091 | 0.78 | SMN1; SMN2 (0.41) | ALDH1A1KDM4ELMNAHPGDTSHR | |
| SCHEMBL6931279 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1KDM4ELMNAHPGDTSHR | |
| SCHEMBL5644282 | 0.78 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNAHPGDTSHR | |
| SCHEMBL10106951 | 0.78 | ATM (0.39) | ALDH1A1HPGDHIF1AEGFRSMN1; SMN2 | |
| SCHEMBL5160384 | 0.77 | MAPT (0.40) | ALDH1A1KDM4ELMNATSHRMAPK1 | |
| SCHEMBL7501188 | 0.77 | SMN1; SMN2 (0.34) | ALDH1A1KDM4ELMNATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097155-B1 | PHOTOCHROMIC SIX-MEMBERED HETEROCYCLIC-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2002-09-18 | — | — | EP | disclosed |
| US-6022497-A | NAPHTHOPYRAN COMPOUNDS WHEN EXPOSED TO ELECTROMAGNETIC RADIATION CONTAINING ULTRAVIOLET RAYS, EXHIBIT A REVERSIBLE CHANGE IN COLOR AND WHEN ULTRAVIOLET RADIATION DISCONTINUED THE PHOTOCHROMIC COMPOUND WILL RETURN TO COLORLESS STATE | PPG INDUSTRIES OHIO, INC. (US) | 2000-02-08 | — | — | US | disclosed |