Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598162 | 0.90 | CTSS (0.42) | CTSSCTSKPTPN1SCN9AKDM4E | |
| SCHEMBL4598164 | 0.83 | CTSS (0.42) | CTSSCTSKPTPN1SCN9AANO1 | |
| SCHEMBL4598878 | 0.82 | CTSS (0.43) | CTSSCTSKPTPN1SCN9AANO1 | |
| SCHEMBL4598249 | 0.80 | CTSS (0.42) | CTSSCTSKPTPN1SCN9AANO1 | |
| SCHEMBL4598492 | 0.80 | CTSS (0.41) | CTSSCTSKPTPN1SCN9AANO1 | |
| SCHEMBL4601576 | 0.79 | CTSS (0.42) | CTSSCTSKPTPN1SCN9AANO1 | |
| SCHEMBL4596925 | 0.78 | CTSS (0.53) | CTSSCTSKPTPN1SCN9ASCN10A | |
| SCHEMBL4917991 | 0.76 | CTSS (0.46) | CTSSCTSKPTPN1SCN9ASCN10A | |
| SCHEMBL4917998 | 0.76 | CTSS (0.46) | CTSSCTSKPTPN1SCN9ASCN10A | |
| SCHEMBL4600120 | 0.74 | CTSS (0.48) | CTSSCTSKPTPN1SCN9ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910274-A1 | PHENYL COMPOUNDS | Eli Lilly and Company (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007015807-A1 | PHENYL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2007-02-08 | — | — | WO | disclosed |