Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596927 | 0.90 | CTSS (0.43) | CTSSCTSKPTPN1SCN9AMEN1 | |
| SCHEMBL4598249 | 0.83 | CTSS (0.42) | CTSSCTSKLMNAPTPN1SCN9A | |
| SCHEMBL4598878 | 0.81 | CTSS (0.43) | CTSSCTSKPTPN1SCN9AMET | |
| SCHEMBL4598164 | 0.80 | CTSS (0.42) | CTSSCTSKPTPN1SCN9ARAB9A | |
| SCHEMBL4598492 | 0.79 | CTSS (0.41) | CTSSCTSKLMNAPTPN1SCN9A | |
| SCHEMBL4598158 | 0.78 | CTSS (0.52) | CTSSCTSKLMNAPTPN1SCN9A | |
| SCHEMBL4601576 | 0.77 | CTSS (0.42) | CTSSCTSKLMNAPTPN1SCN9A | |
| SCHEMBL4929526 | 0.76 | CTSK (0.46) | CTSSCTSKLMNAPTPN1SCN9A | |
| SCHEMBL4929520 | 0.76 | CTSK (0.46) | CTSSCTSKLMNAPTPN1SCN9A | |
| SCHEMBL4600120 | 0.73 | CTSS (0.48) | CTSSCTSKLMNAPTPN1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910274-A1 | PHENYL COMPOUNDS | Eli Lilly and Company (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007015807-A1 | PHENYL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2007-02-08 | — | — | WO | disclosed |