Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575118 | 0.89 | HCRTR1 (0.30) | HCRTR1HCRTR2 | |
| SCHEMBL4574346 | 0.89 | HTT (0.34) | HCRTR2LMNAHPGDSMN1; SMN2 | |
| SCHEMBL4596912 | 0.89 | LMNA (0.35) | LMNAHPGDSMN1; SMN2 | |
| SCHEMBL4595427 | 0.88 | LMNA (0.35) | LMNAHPGDSMN1; SMN2 | |
| SCHEMBL4574395 | 0.86 | HCAR2 (0.35) | — | |
| SCHEMBL4573882 | 0.82 | SMN1; SMN2 (0.34) | HCRTR1HPGDSMN1; SMN2 | |
| SCHEMBL4574391 | 0.76 | MEN1 (0.30) | — | |
| SCHEMBL4574534 | 0.75 | CYP3A4 (0.31) | — | |
| SCHEMBL4574083 | 0.73 | TSHR (0.40) | LMNAHPGDSMN1; SMN2 | |
| SCHEMBL4574520 | 0.72 | SMN1; SMN2 (0.38) | HCRTR1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071766-A2 | SPIRO-INDENE SUBSTITUTED IMIDAZONAPHYTHYRIDINE AND PYRANOIMIDAZOPYRIDINE DERIVATIVES AS INHIBITORS OF GASTRIC ACID SECRETION | NYCOMED GMBH (DE) | 2008-06-19 | — | — | WO | disclosed |