Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650698 | 0.86 | SMN1; SMN2 (0.35) | MYCHTR7 | |
| SCHEMBL4596881 | 0.75 | NOTUM (0.36) | HRH4 | |
| SCHEMBL4596565 | 0.68 | PARP1 (0.53) | HTR1ADRD2HTR7 | |
| SCHEMBL6047905 | 0.67 | HTR1A (0.43) | HTR1ADRD2HTR7 | |
| SCHEMBL4596563 | 0.67 | HTR1A (0.38) | MYCHTR1ADRD2HTR7 | |
| SCHEMBL4222094 | 0.66 | PRKAB2 (0.56) | MYCHTR1ADRD2HTR7 | |
| SCHEMBL28899579 | 0.65 | MYC (0.58) | MYCCA1CA2CA7CA9 | |
| SCHEMBL8210984 | 0.64 | PRKAB2 (0.43) | HTR1ADRD2CA2 | |
| SCHEMBL1133067 | 0.63 | MYC (0.56) | MYCCA1CA2CA7CA9 | |
| SCHEMBL4161420 | 0.62 | CA1 (0.48) | MYCCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007509174-A | — | — | 2007-04-12 | — | — | JP | claimed |
| EP-1675840-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2006-07-05 | — | — | EP | claimed |
| WO-2005044812-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | WYETH A CORPORATION OF THE STATE OF DELAWARE (US) | 2005-05-19 | — | — | WO | claimed |
| EP-1874750-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth Incoporated (US) | 2008-01-09 | — | — | EP | disclosed |