Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597187 | 0.86 | MYC (0.39) | HTR7MYC | |
| SCHEMBL4596881 | 0.82 | NOTUM (0.36) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL4648888 | 0.73 | MAOB (0.38) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL20713018 | 0.70 | PARP1 (0.45) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL9378692 | 0.68 | CA12 (0.38) | HTR2AALDH1A1KDM4EHTR7MAPK1 | |
| SCHEMBL6047940 | 0.68 | PARP1 (0.49) | HTR2AHTR2CALDH1A1MAOAMAOB | |
| SCHEMBL598761 | 0.67 | TSHR (0.53) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL30169568 | 0.67 | ACHE (0.64) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL197690 | 0.67 | ACHE (0.64) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL30354037 | 0.67 | ACHE (0.64) | SMN1; SMN2NPC1RAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874750-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth Incoporated (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2007030150-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | WYETH (US) | 2007-03-15 | — | — | WO | disclosed |