Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | IAPP | P10997 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3060044 | 0.88 | MTNR1A (0.55) | LMNAKDM4EMTNR1AMTNR1BMEN1 | |
| SCHEMBL11576902 | 0.84 | IAPP (0.54) | MTNR1AMTNR1BIAPPHMGB1 | |
| SCHEMBL10348018 | 0.84 | ALDH1A1 (0.54) | LMNATAAR1ALDH1A1HPGDMTNR1A | |
| SCHEMBL20562323 | 0.81 | MTNR1A (0.51) | LMNAALDH1A1HPGDKDM4EMTNR1A | |
| SCHEMBL4597216 | 0.81 | NQO2 (0.60) | LMNAHPGDCA1CA2HTT | |
| SCHEMBL6580321 | 0.79 | NPSR1 (0.55) | ALDH1A1HPGDKDM4EHSD17B10IAPP | |
| SCHEMBL4440889 | 0.78 | CNR1 (0.47) | LMNAALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL5309632 | 0.77 | MPO (0.56) | TAAR1KDM4EHSD17B10CA12CA2 | |
| SCHEMBL3652663 | 0.76 | TYR (0.51) | LMNAALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL25282692 | 0.75 | GPR84 (0.58) | LMNAALDH1A1MTNR1AMTNR1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |