Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5124921 | 0.81 | HDAC1 (0.48) | HDAC6HDAC8HDAC1OPRM1OPRK1 | |
| SCHEMBL7038451 | 0.78 | MMP1 (0.55) | ALOX15HTTSMN1; SMN2ADAM17MMP1 | |
| SCHEMBL7038457 | 0.78 | MMP1 (0.55) | ALOX15HTTSMN1; SMN2ADAM17MMP1 | |
| SCHEMBL4596780 | 0.73 | HDAC8 (0.51) | HDAC6HDAC8HDAC1 | |
| SCHEMBL13632802 | 0.73 | HPGD (0.53) | HTTSMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL4984200 | 0.73 | HPGD (0.53) | HTTSMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL21628436 | 0.71 | HDAC6 (0.59) | HDAC6ALOX15HTTSMN1; SMN2ADAM17 | |
| Hydrochloric Acid SCHEMBL6261119 | 0.71 | GAA (0.51) | HTTALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL5007669 | 0.71 | DPP4 (0.54) | HPGDKMT2AHRH2HRH1TSHR | |
| SCHEMBL14027830 | 0.71 | DPP4 (0.54) | HPGDKMT2AHRH2HRH1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200521-A1 | Novel hydroxamic acid containing amino acid derivatives | BEXEL PHARMACEUTICALS. INC. | 2008-08-21 | — | — | US | claimed |
| EP-1906731-A2 | NOVEL HYDROXAMIC ACID-CONTAINING AMINO ACID DERIVATIVES | Bexel Pharmaceuticals Inc (US) | 2008-04-09 | — | — | EP | claimed |
| WO-2007005603-A2 | NOVEL HYDROXAMIC ACID-CONTAINING AMINO ACID DERIVATIVES | BEXEL PHARMACEUTICALS, INC. (US) | 2007-01-11 | — | — | WO | claimed |
| US-20070004776-A1 | Novel hydroxamic acid-containing amino acid derivatives | BEXEL PHARMACEUTICALS, INC. | 2007-01-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200521-A1 | Novel hydroxamic acid containing amino acid derivatives | HGFAC, HCAR2, BCAT1 | HDAC6 639/4885ALOX15 250/4885HTT 1203/4885 |
| US-20070004776-A1 | Novel hydroxamic acid-containing amino acid derivatives | HGFAC, HCAR2, BCAT1 | HDAC6 684/4885ALOX15 295/4885HTT 1074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.