Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.47 |
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038451 | 1.00 | MMP1 (0.55) | MMP1MMP3MMP13ADAM17HPGD | |
| SCHEMBL365418 | 0.82 | HPGD (0.51) | MMP1MMP3MMP13ADAM17HPGD | |
| SCHEMBL13267430 | 0.82 | HPGD (0.51) | MMP1MMP3MMP13ADAM17HPGD | |
| SCHEMBL10179952 | 0.82 | HPGD (0.51) | MMP1MMP3MMP13ADAM17HPGD | |
| SCHEMBL12324842 | 0.82 | HPGD (0.51) | MMP1MMP3MMP13ADAM17HPGD | |
| SCHEMBL371088 | 0.82 | HPGD (0.51) | MMP1MMP3MMP13ADAM17HPGD | |
| Hydrochloric Acid SCHEMBL295178 | 0.81 | HPGD (0.50) | MMP1MMP3MMP13ADAM17HPGD | |
| SCHEMBL13632802 | 0.79 | HPGD (0.53) | HPGDSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL4984200 | 0.79 | HPGD (0.53) | HPGDSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL4597495 | 0.78 | HDAC6 (0.44) | MMP1MMP3MMP13ADAM17HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659737-B1 | Catecholamine surrogates useful as beta 3 agonists | BRISTOL MYERS SQUIBB CO (US) | 2003-03-26 | — | — | EP | disclosed |
| US-5776983-A | ANTIDIABETIC AGENTS, OBESITY, GASTROINTESTINAL DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0659737-A2 | Catecholamine surrogates useful as B3 agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-28 | — | — | EP | disclosed |