Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31391953 | 1.00 | L3MBTL1 (0.53) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11764831 | 0.86 | KDM4E (0.48) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL5539094 | 0.81 | L3MBTL1 (0.53) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL31621296 | 0.80 | KCNN4 (0.48) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3256218 | 0.80 | KCNN4 (0.48) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL15250195 | 0.80 | L3MBTL1 (0.41) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL1485201 | 0.77 | CYP1A2 (0.56) | TDP1ALDH1A1MAPTLMNAHTT | |
| SCHEMBL3727472 | 0.77 | L3MBTL1 (0.50) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3731507 | 0.77 | ALDH1A1 (0.55) | L3MBTL1TDP1KMT2AALDH1A1MAPT | |
| SCHEMBL13684907 | 0.77 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11377434-B2 | Methods for preparing substituted chromanone derivatives | HANGZHOU DUYI TECHNOLOGY CO. LTD. (CN) | 2022-07-05 | — | — | US | disclosed |
| WO-2022016309-A1 | METHODS FOR PREPARING SUBSTITUTED CHROMANONE DERIVATIVES | HANGZHOU DUYI TECHNOLOGY CO. LTD. (CN) | 2022-01-27 | — | — | WO | disclosed |
| US-20220024890-A1 | METHODS FOR PREPARING SUBSTITUTED CHROMANONE DERIVATIVES | HANGZHOU DUYI TECHNOLOGY CO. LTD. (CN) | 2022-01-27 | — | — | US | disclosed |
| EP-1786823-B1 | ALKYLIDENE TETRAHYDRONAPHTHALENE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BAYER SCHERING PHARMA AG (DE) | 2008-01-16 | — | — | EP | disclosed |
| CN-101087780-A | Tricyclic amino alcohols, processes for synthesis of same and use of same as anti-inflammatory drugs | BAYER SCHERING PHARMA AG (DE) | 2007-12-12 | — | — | CN | disclosed |
| CN-101065386-A | Alkylidene-tetrahydronaphthalene derivatives, process for their preparation and their use as anti-inflammatory agents | SCHERING AG (DE) | 2007-10-31 | — | — | CN | disclosed |
| EP-1786823-A1 | ALKYLIDENE TETRAHYDRONAPHTHALENE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2007-05-23 | — | — | EP | disclosed |
| US-20060167025-A1 | Tricyclic amino alcohols, processes for synthesis of same and use of same as anti-inflammatory drugs | SCHERING AG (DE) | 2006-07-27 | — | — | US | disclosed |
| WO-2006066950-A2 | TRICYCLIC AMINOALCOHOLS, METHODS FOR PRODUCING THE SAME AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-06-29 | — | — | WO | disclosed |
| US-20060084652-A1 | Alkylidene-tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | SCHERING AG (DE) | 2006-04-20 | — | — | US | disclosed |
| WO-2006027236-A1 | ALKYLIDENE TETRAHYDRONAPHTHALENE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167025-A1 | Tricyclic amino alcohols, processes for synthesis of same and use of same as anti-inflammatory drugs | ALDH7A1, NOTUM, GOT2 | L3MBTL1 4874/4885TDP1 2506/4885KMT2A 3173/4885 |
| US-20060084652-A1 | Alkylidene-tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | PTGES, PTGS1, PTGES2 | L3MBTL1 4871/4885TDP1 3064/4885KMT2A 4743/4885 |
| US-20220024890-A1 | METHODS FOR PREPARING SUBSTITUTED CHROMANONE DERIVATIVES | CBR3, CYP2F1, CBR1 | L3MBTL1 4174/4885TDP1 2358/4885KMT2A 3543/4885 |
| US-11377434-B2 | Methods for preparing substituted chromanone derivatives | CYP2E1, CYP2F1, CBR1 | L3MBTL1 3937/4885TDP1 1785/4885KMT2A 3579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.