Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UPP1 | Q16831 | 1/20 | 0.34 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1801170 | 0.72 | — | — | |
| SCHEMBL8086262 | 0.69 | ALDH1A1 (0.38) | UPP1HAVCR2KDM4ERECQLTDP1 | |
| SCHEMBL8087591 | 0.65 | LOXL2 (0.39) | UPP1HAVCR2KDM4ERECQLTDP1 | |
| SCHEMBL4448267 | 0.64 | UPP1 (0.34) | UPP1HAVCR2KDM4ERECQLTDP1 | |
| SCHEMBL3969844 | 0.60 | KDM4E (0.34) | KDM4EALDH1A1GAAHPGDALOX15 | |
| SCHEMBL18394364 | 0.60 | ENPP2 (0.46) | TSHRALDH1A1 | |
| SCHEMBL855530 | 0.60 | ENPP2 (0.41) | UPP1HAVCR2KDM4ERECQLTDP1 | |
| SCHEMBL1232734 | 0.59 | IMPDH2 (0.51) | — | |
| SCHEMBL20500455 | 0.59 | IMPDH2 (0.47) | — | |
| SCHEMBL15367361 | 0.58 | TSHR (0.37) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1909785-A2 | USE OF PROGESTERONE RECEPTOR MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2008-04-16 | — | — | EP | disclosed |
| EP-1910285-A1 | CYANOPYRROLE-SULFONAMIDE PROGESTERONE RECEPTOR MODULATORS AND USES THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007016212-A1 | CYANOPYRROLE-SULFONAMIDE PROGESTERONE RECEPTOR MODULATORS AND USES THEREOF | WYETH (US) | 2007-02-08 | — | — | WO | disclosed |
| WO-2007016385-A2 | USE OF SUBSTITUTED 5-AMINO-1H-PYRROLE-2-CARBONITRILE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2007-02-08 | — | — | WO | disclosed |