Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 12/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17118647 | 0.77 | AAK1 (0.37) | AAK1KDRFLT1MAPT | |
| SCHEMBL17118650 | 0.77 | AAK1 (0.38) | AAK1KDRFLT1 | |
| SCHEMBL4597509 | 0.76 | LMNA (0.40) | AAK1AKT1MAPT | |
| SCHEMBL3710918 | 0.74 | CTSS (0.41) | AAK1AKT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24944947 | 0.73 | EPAS1 (0.39) | AAK1 | |
| SCHEMBL4595970 | 0.72 | CTSL (0.41) | AKT1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27945122 | 0.72 | AAK1 (0.38) | AAK1TRPA1 | |
| SCHEMBL253236 | 0.72 | AAK1 (0.50) | AAK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27945123 | 0.72 | AAK1 (0.50) | AAK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15315931 | 0.72 | AAK1 (0.38) | AAK1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |