Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710918 | 0.87 | CTSS (0.41) | LMNARXFP1POLBAAK1HPGD | |
| SCHEMBL4595970 | 0.87 | CTSL (0.41) | HPGDRORCMAPTAKT1KDM4E | |
| SCHEMBL17018582 | 0.81 | CYP2C19 (0.44) | LMNARXFP1POLBAAK1HPGD | |
| SCHEMBL4597866 | 0.76 | AAK1 (0.40) | AAK1MAPTAKT1 | |
| SCHEMBL4553418 | 0.73 | GPR119 (0.39) | LMNARXFP1POLBKMT2AMEN1 | |
| SCHEMBL24944947 | 0.73 | EPAS1 (0.39) | AAK1GAA | |
| SCHEMBL29770797 | 0.71 | CA12 (0.44) | KMT2AMEN1ATMAKT1GAA | |
| SCHEMBL3726743 | 0.70 | GAA (0.42) | LMNARXFP1POLBKMT2AMEN1 | |
| SCHEMBL19879722 | 0.70 | CTSL (0.39) | MAPTAKT1KDM4EGAAPKM | |
| SCHEMBL10216897 | 0.70 | RXFP1 (0.48) | RXFP1POLBKMT2AMEN1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |