Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.35 |
| ▸ | CASP2 | P42575 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | F13A1 | P00488 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | THPO | P40225 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802610 | 0.93 | GNAI3 (0.42) | GNAI3GNAO1GNAI1DPP7DNM1 | |
| SCHEMBL3672040 | 0.92 | CA12 (0.44) | CASP2MEN1KMT2ACA12F13A1 | |
| SCHEMBL10882426 | 0.91 | GNAI3 (0.45) | GNAI3GNAO1GNAI1DPP7DNM1 | |
| SCHEMBL10439956 | 0.86 | — | — | |
| SCHEMBL8644870 | 0.86 | RRM1 (0.36) | GNAI3GNAO1GNAI1DPP7TSHR | |
| SCHEMBL308611 | 0.86 | OPRM1 (0.39) | DPP7CA12CA2ALOX15CA7 | |
| SCHEMBL6021971 | 0.85 | GNAI3 (0.47) | GNAI3GNAO1GNAI1DPP7DNM1 | |
| SCHEMBL27832222 | 0.84 | OPRM1 (0.37) | DPP7CA12CA2ALOX15CA7 | |
| SCHEMBL28158597 | 0.83 | CA12 (0.39) | DPP7CASP2MEN1KMT2ACA12 | |
| SCHEMBL28474328 | 0.82 | GNAI3 (0.36) | GNAI3GNAO1GNAI1DPP7DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877419-A2 | POLYMORPHIC AND AMORPHOUS SALT FORMS OF SQUALAMINE DILACTATE | Genaera Corporation (US) | 2008-01-16 | — | — | EP | claimed |
| WO-2006116309-A2 | POLYMORPHIC AND AMORPHOUS SALT FORMS OF SQUALAMINE DILACTATE | GENAERA CORPORATION (US) | 2006-11-02 | — | — | WO | claimed |
| EP-1877419-A2 | POLYMORPHIC AND AMORPHOUS SALT FORMS OF SQUALAMINE DILACTATE | Genaera Corporation (US) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006116309-A2 | POLYMORPHIC AND AMORPHOUS SALT FORMS OF SQUALAMINE DILACTATE | GENAERA CORPORATION (US) | 2006-11-02 | — | — | WO | disclosed |
| EP-1051244-A4 | METHOD AND ARTICLES FOR TRANSFECTION OF GENETIC MATERIAL | TOMALIA DONALD A (US) | 2003-06-11 | — | — | EP | disclosed |
| EP-0912584-B1 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | HOFFMANN LA ROCHE (CH) | 2002-12-18 | — | — | EP | disclosed |
| EP-1051244-A1 | METHOD AND ARTICLES FOR TRANSFECTION OF GENETIC MATERIAL | THE DOW CHEMICAL COMPANY (US) | 2000-11-15 | — | — | EP | disclosed |
| US-6022892-A | Bis-platinum complexes with polyamine ligands as antitumor agents | HOFFMAN-LA ROCHE INC. (US) | 2000-02-08 | — | — | US | disclosed |
| WO-1999034908-A1 | METHOD AND ARTICLES FOR TRANSFECTION OF GENETIC MATERIAL | THE DOW CHEMICAL COMPANY (US) | 1999-07-15 | — | — | WO | disclosed |
| EP-0912584-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998003519-A9 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | — | 1998-07-16 | — | — | WO | disclosed |
| WO-1998003519-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-29 | — | — | WO | disclosed |