⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1735138 | 0.77 | PDGFRB (0.49) | — | |
| SCHEMBL6412792 | 0.77 | CYP1A1 (0.55) | — | |
| SCHEMBL2599589 | 0.76 | PIN1 (0.55) | — | |
| SCHEMBL15709858 | 0.76 | ALKBH1 (0.49) | — | |
| SCHEMBL23882512 | 0.75 | KDM4E (0.33) | — | |
| SCHEMBL7993944 | 0.74 | — | — | |
| SCHEMBL3825167 | 0.74 | FTO (0.42) | — | |
| SCHEMBL160948 | 0.74 | NQO1 (0.48) | — | |
| SCHEMBL2221457 | 0.74 | PLAU (0.38) | — | |
| SCHEMBL15709596 | 0.73 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 651 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110330461-A | A kind of preparation method of 2- chloro-5-methoxyl pyrimidine | 苏州莱安医药化学技术有限公司 | 2019-10-15 | — | — | CN | claimed |
| CN-110294715-A | Synthesis method of 2,4, 6-trichloro-5-methoxypyrimidine | 南京普锐达医药科技有限公司 | 2019-10-01 | — | — | CN | claimed |
| CN-110106700-A | A kind of cellulose base fiber fabric anti-pilling finishing liquid and method for sorting | 苏州大学 | 2019-08-09 | — | — | CN | claimed |
| CN-110041269-A | A kind of preparation method of the chloro- 5- hydroxy pyrimidine of 2- | 海门瑞一医药科技有限公司 | 2019-07-23 | — | — | CN | claimed |
| CN-102516183-A | Method for preparing sulfadoxine and its intermediate | CHANGSHU NANHU IND CHEMICAL CO LTD | 2012-06-27 | — | — | CN | claimed |
| CN-102432550-A | Preparation method of sulfadoxine and intermediate thereof | CHANGSHU NANHU IND CHEMICAL CO LTD | 2012-05-02 | — | — | CN | claimed |
| CN-102304095-A | Preparation method of sulfadoxine | CHANGSHU NANHU IND CHEMICAL CO LTD | 2012-01-04 | — | — | CN | claimed |
| CN-102304094-A | Preparation method of sulfadoxine and intermediate thereof | CHANGSHU NANHU IND CHEMICAL CO LTD | 2012-01-04 | — | — | CN | claimed |
| CN-101486684-B | Preparation of 2,4-dichloro-5-methoxy pyrimidine | CHANGZHOU HUAYI CHEMICAL CO LTD | 2010-11-10 | — | — | CN | claimed |
| CN-101486684-A | Preparation of 2,4-dichloro-5-methoxy pyrimidine | CHANGZHOU HUAYI CHEMICAL CO LT (CN) | 2009-07-22 | — | — | CN | claimed |
| US-20260138991-A1 | SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES | MOMA THERAPEUTICS INC (US) | 2026-05-21 | — | — | US | disclosed |
| US-12590071-B2 | Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2026-03-31 | — | — | US | disclosed |
| EP-4705298-A2 | SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES | Moma Therapeutics, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2026041663-A1 | P2X7 RECEPTOR ANTAGONISTS | BREYE THERAPEUTICS APS (DK) | 2026-02-26 | — | — | WO | disclosed |
| US-12559508-B2 | Semi-saturated bicyclic derivatives and related uses | MOMA THERAPEUTICS, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| CN-1111242-A | Benzenesulfonamide derivative and process for preparing thereof | TANABE SEIYAKU CO (JP) | 1995-11-08 | — | — | CN | disclosed |
| EP-0658548-A1 | Benzenesulfonamide derivative and process for preparing thereof | TANABE SEIYAKU CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |
| CN-1085556-A | The 4-pyrimidyl and the pyridinyl derivatives of the indol-3-yl alkylpiperazine of anti-migraine | BRISTOL MYERS SQUIBB CO (US) | 1994-04-20 | — | — | CN | disclosed |
| US-4560689-A | ANTICONVULSANTS, ANTIDEPRESSANTS, SEDATIVE ANTIDOTES, AND ANTIEPLILEPTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1985-12-24 | — | — | US | disclosed |
| US-4479955-A | ANTICONVULSANTS, ANTIDEPRESSANTS, ANTIEPILEPTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |