Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.60 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260174 | 0.85 | ALB (0.56) | ALBP2RX1P2RX7CES2CES1 | |
| SCHEMBL19235964 | 0.82 | HSP90AB1 (0.48) | ALBCES2CES1HSP90AB1MEN1 | |
| SCHEMBL31599609 | 0.82 | CES2 (0.61) | ALBCES2CES1BCHEHSP90AB1 | |
| SCHEMBL633282 | 0.82 | CES2 (0.61) | ALBCES2CES1BCHEHSP90AB1 | |
| SCHEMBL1155949 | 0.82 | PTPN1 (0.58) | CES2CES1RXFP1PTPN1ERCC5 | |
| SCHEMBL30036725 | 0.82 | PTPN1 (0.58) | CES2CES1RXFP1PTPN1ERCC5 | |
| SCHEMBL1606580 | 0.80 | HSP90AB1 (0.55) | HSP90AB1MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL9118756 | 0.79 | CES2 (0.47) | ALBCES2CES1BCHEHSP90AB1 | |
| SCHEMBL4103677 | 0.79 | PDK2 (0.43) | ALBCES2CES1BCHERXFP1 | |
| SCHEMBL17858663 | 0.79 | CES2 (0.42) | ALBCES2CES1BCHEHSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1662518-A | Process for preparing epoxytriazole derivatives and intermediates used therein | SUMITOMO CHEMICAL CO (JP) | 2005-08-31 | — | — | CN | claimed |
| US-20220162209-A1 | SALICYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2022-05-26 | — | — | US | disclosed |
| CN-109574945-A | Isoxazoline derivative and its application in agricultural | 东莞东阳光科研发有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-102245587-A | Trpv1 antagonists | ABBOTT LAB | 2011-11-16 | — | — | CN | disclosed |
| CN-102186836-A | Trpv1 antagonists | ABBOTT LAB | 2011-09-14 | — | — | CN | disclosed |
| CN-101827585-A | Solid dispersion product containing N-aryl ureido compound | ABBOTT GMBH & CO KG | 2010-09-08 | — | — | CN | disclosed |
| CN-100503544-C | Intermediate for producing epoxytriazole derivative | SUMITOMO CHEMICAL CO (JP) | 2009-06-24 | — | — | CN | disclosed |
| EP-1786823-B1 | ALKYLIDENE TETRAHYDRONAPHTHALENE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BAYER SCHERING PHARMA AG (DE) | 2008-01-16 | — | — | EP | disclosed |
| EP-1861379-A1 | TETRAHYDRONAPHTHALENE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2007-12-05 | — | — | EP | disclosed |
| CN-1970522-A | Production methods of epoxytriazole derivative and intermediate therefor | SUMITOMO CHEMICAL CO (JP) | 2007-05-30 | — | — | CN | disclosed |
| CN-1298711-C | Process for preparing epoxytriazole derivatives and intermediates used therein | SUMITOMO CHEMICAL CO (JP) | 2007-02-07 | — | — | CN | disclosed |
| US-20060229305-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | SCHERING AG (DE) | 2006-10-12 | — | — | US | disclosed |
| WO-2006100100-A1 | TETRAHYDRONAPHTHALENE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-09-28 | — | — | WO | disclosed |
| US-20060084652-A1 | Alkylidene-tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | SCHERING AG (DE) | 2006-04-20 | — | — | US | disclosed |
| WO-2006027236-A1 | ALKYLIDENE TETRAHYDRONAPHTHALENE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-03-16 | — | — | WO | disclosed |
| CN-1662518-A | Process for preparing epoxytriazole derivatives and intermediates used therein | SUMITOMO CHEMICAL CO (JP) | 2005-08-31 | — | — | CN | disclosed |
| CN-1087017-C | Azole compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-07-03 | — | — | CN | disclosed |
| CN-1175950-A | Azole compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-03-11 | — | — | CN | disclosed |
| EP-0809640-A1 | AZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025410-A1 | AZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084652-A1 | Alkylidene-tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | PTGES, PTGS1, PTGES2 | ALB 1573/4885P2RX1 1042/4885P2RX7 810/4885 |
| US-20220162209-A1 | SALICYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF | ADSL, SLC35B2, ADORA1 | ALB 1823/4885P2RX1 215/4885P2RX7 183/4885 |
| US-20060229305-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | PTGES, TNF, DHPS | ALB 2228/4885P2RX1 1313/4885P2RX7 991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.