Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.38 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597034 | 0.91 | ESR2 (0.39) | NR1H2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL1750511 | 0.82 | ESR2 (0.53) | NR1H2MAPTMAPK1CHRM2CHRM4 | |
| SCHEMBL951478 | 0.81 | NR1H2 (0.47) | NR1H2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3197517 | 0.81 | SLC6A3 (0.54) | NR1H2HTTCHRM2CHRM4CHRM5 | |
| SCHEMBL6418231 | 0.81 | CHRM5 (0.59) | NR1H2MAPK1CHRM2CHRM4CHRM5 | |
| SCHEMBL9350724 | 0.79 | GPR119 (0.47) | NR1H2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3205498 | 0.79 | GPR119 (0.49) | NR1H2ALDH1A1MAPTCHRM2CHRM4 | |
| SCHEMBL3194232 | 0.79 | SLC6A3 (0.57) | NR1H2ESR2SLC6A2 | |
| SCHEMBL4598190 | 0.77 | REN (0.35) | GPR119 | |
| SCHEMBL4598116 | 0.77 | NR1H2 (0.42) | NR1H2CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908471-A1 | Tetrahydropyridines as renin inhibitors | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |